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ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test

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ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test

Also known as: ITGAM Gene Test, Lupus Susceptibility Test, SLE Genetic Test

ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect genetic variations in the ITGAM gene associated with increased susceptibility to systemic lupus erythematosus (SLE), aiding in risk assessment, differential diagnosis, and personalized management.

Test Code
5144
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide clinical history and family pedigree during genetic counseling session.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

Sample collected via venipuncture for blood or application of one drop on FTA card.

Step 3

Report Delivery

Sample transported at ambient temperature; wait for report delivery in 3-4 weeks.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling to draw pedigree chart and provide clinical history.
2
During the Test:Sample collection via blood draw or FTA card using NGS technology.
3
After the Test:Report delivered in 3-4 weeks via online portal, email, or WhatsApp.

About This Test

Who Should Get This Test

To detect genetic variations in the ITGAM gene associated with increased susceptibility to systemic lupus erythematosus (SLE), aiding in risk assessment, differential diagnosis, and personalized management.

How to Prepare

  • Blood sample: Collect via venipuncture in EDTA tube
  • FTA Card: Apply one drop of blood and air dry
  • Ensure proper labeling and transport at ambient temperature

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for lupus susceptibility can aid in early risk assessment and personalized management, especially for individuals with family history or unclear symptoms."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA Card
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient volume
  • Improperly labeled

Understanding Your Results

Results indicate the presence or absence of genetic variations in the ITGAM gene associated with lupus susceptibility.
Positive result: Indicates presence of ITGAM variants associated with increased lupus risk
Negative result: No known pathogenic variants detected, but does not rule out lupus
Variant of uncertain significance: May require further genetic counseling and testing
⚠️ When to Consult a Doctor:

If results indicate increased genetic risk or if autoimmune symptoms persist, consult a healthcare provider for further evaluation.

Limitations

  • Test only assesses genetic susceptibility, not definitive diagnosis
  • Other genes and environmental factors contribute to lupus
  • Results may not predict disease onset or severity

Risks & Considerations

  • Minor bruising at blood draw site
  • Potential psychological impact of genetic risk information

Interfering Factors

  • Sample contamination
  • Degraded DNA
  • Technical sequencing errors

Frequently Asked Questions

What is the ITGAM Gene SLE Susceptibility Test?
It is an NGS genetic test that analyzes variations in the ITGAM gene to assess susceptibility to systemic lupus erythematosus (SLE).
Who should consider this test?
Individuals with a family history of lupus, unclear autoimmune symptoms, or suspected genetic predisposition to SLE.
How is the test performed?
A blood sample or DNA is collected and analyzed using Next Generation Sequencing technology to detect ITGAM gene variations.
What does a positive result mean?
A positive result indicates the presence of genetic variations associated with increased risk of developing lupus, but it does not diagnose the disease.
What is the cost of the test?
The test costs INR 20000, with free home sample collection available across India.
Is home collection available?
Yes, DNA Labs India offers free home sample collection for this test in numerous cities across India.
How long does it take to get results?
Results are typically delivered within 3 to 4 weeks after sample collection.
Is the test covered by insurance?
Coverage depends on your insurance plan; it is not universally covered. Check with your provider.
What are the limitations of the test?
The test only assesses genetic susceptibility and does not diagnose lupus definitively; other factors like environment also play a role.
Can this test diagnose lupus?
No, this test assesses genetic risk but cannot diagnose lupus; clinical evaluation and other tests are needed for diagnosis.
What is the role of the ITGAM gene in lupus?
The ITGAM gene codes for CD11b protein, involved in immune response; variations can lead to abnormal immune function and increased lupus susceptibility.
How accurate is the NGS Genetic Test?
NGS technology is highly accurate for detecting genetic variations, but results should be interpreted in conjunction with clinical history and other tests.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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