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DNA Labs India

JAK2 Gene (V617F) Quantitative Test

DNA Labs India | ISO 9001:2015 Certified

JAK2 Gene (V617F) Quantitative Test

Short Name: JAK2 V617F Quantitative

Also known as: JAK2 V617F Mutation Test, JAK2 Quantitative Test

JAK2 Gene (V617F) Quantitative Test test available at DNA Labs India for ₹6,000. Uses Real Time PCR on Bone marrow / Peripheral blood samples. Results in 3-4 days. Free home collection in 300+ cities across India.

Genetic Test🏠 Home Collection

🩺 Medically Reviewed By

Overview

To diagnose polycythemia vera and other myeloproliferative neoplasms by detecting and quantifying the JAK2 V617F mutation.

Test Code
3057
Price
₹6,000
Sample Type
Bone marrow / Peripheral blood
Result Time
3-4 days
Fasting Required
No
Method
Real Time PCR
Step 1

Sample Collection

No special preparation required. Inform your doctor about any medications or recent procedures.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm. For bone marrow, a biopsy may be performed.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Avoid strenuous activity for a few hours.

Timeline: 3-4 days

Patient Instructions

1
Before the Test:No special preparation required. Inform your doctor about any medications or recent procedures.
2
During the Test:A blood sample will be drawn from a vein in your arm. For bone marrow, a biopsy may be performed.
3
After the Test:Apply pressure to the puncture site to stop bleeding. Avoid strenuous activity for a few hours.

About This Test

Who Should Get This Test

To diagnose polycythemia vera and other myeloproliferative neoplasms by detecting and quantifying the JAK2 V617F mutation.

How to Prepare

  • Bring doctor's prescription
  • Wear loose clothing
  • Stay hydrated

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"The JAK2 V617F quantitative test is essential for accurate diagnosis and monitoring of polycythemia vera, helping to tailor treatment plans for patients."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBone marrow / Peripheral blood
Sample Volume2 ml
ContainerEDTA Vacutainer
Collection MethodVenipuncture

Sample Stability

Blood sample: stable for 24 hours at room temperature
Bone marrow: process immediately
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient sample volume
  • Incorrect container

Understanding Your Results

Results indicate the presence and quantity of the JAK2 V617F mutation.
📊

Positive

JAK2 V617F mutation detected, suggestive of MPN

📊

Negative

No JAK2 V617F mutation detected

📊

Quantitative

Percentage of mutant allele; higher levels may indicate disease severity

⚠️ When to Consult a Doctor:

If test results are positive or if symptoms persist, consult a hematologist or oncologist for further evaluation and treatment.

Limitations

  • May not detect all JAK2 mutations
  • Requires confirmation with other tests
  • Quantitative results may vary

Risks & Considerations

  • Minor bruising at puncture site
  • Rare infection
  • Discomfort during bone marrow biopsy

Interfering Factors

  • Sample contamination
  • Improper sample storage
  • Recent blood transfusion

Frequently Asked Questions

What is the JAK2 Gene V617F Quantitative Test?
It is a blood test that detects and measures the JAK2 V617F mutation, commonly associated with polycythemia vera and other myeloproliferative neoplasms.
Why is this test done?
To diagnose polycythemia vera, monitor disease progression, and guide treatment decisions for myeloproliferative neoplasms.
How is the test performed?
A blood or bone marrow sample is collected and analyzed using real-time PCR to quantify the JAK2 V617F mutation.
What is the cost of the test in India?
The cost is approximately INR 6000, with free home sample collection available in many cities.
Is home collection available?
Yes, free home sample collection is offered for online bookings across India.
How long does it take to get results?
Results are typically available within 3-4 days.
What do positive results mean?
Positive results indicate the presence of the JAK2 V617F mutation, which may suggest polycythemia vera or another myeloproliferative neoplasm.
What are the symptoms of polycythemia vera?
Symptoms include fatigue, weakness, shortness of breath, headaches, dizziness, blurred vision, unexplained weight loss, enlarged spleen or liver, and unexplained bruising or bleeding.
Do I need a doctor's prescription for this test?
Yes, a doctor's prescription is required, except for surgery, pregnancy cases, or people planning to travel abroad.
Are there any risks associated with the test?
Risks are minimal and may include minor bruising at the puncture site or rare infection.
How should I prepare for the test?
No special preparation is needed. Inform your doctor about any medications or recent procedures.
What other tests might be needed if this test is positive?
Additional tests such as complete blood count, bone marrow biopsy, or other genetic tests may be recommended to confirm diagnosis and assess disease stage.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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