KIT Gene Leukemia, acute myeloid NGS Genetic Test
Short Name: KIT Gene AML NGS
Also known as: KIT Gene Mutation Analysis, KIT NGS Panel, Acute Myeloid Leukemia Genetic Test
KIT Gene Leukemia, acute myeloid NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are delivered within 3 to 4 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the KIT gene that are associated with acute myeloid leukemia. It helps in confirming diagnosis, assessing prognosis, and guiding treatment decisions, particularly in patients with AML who may benefit from targeted therapy.
- Test Code
- 5999
- CPT Code
- 81445
- ICD Code
- C92.00
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are delivered within 3 to 4 weeks after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No special preparation required. However, a clinical history and genetic counseling session are recommended before the test.
Method: Venipuncture or Fingerstick
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. If using FTA card, a fingerstick blood drop is collected.
Report Delivery
You may resume normal activities immediately. No restrictions.
Timeline: Reports are delivered within 3 to 4 weeks after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the KIT gene that are associated with acute myeloid leukemia. It helps in confirming diagnosis, assessing prognosis, and guiding treatment decisions, particularly in patients with AML who may benefit from targeted therapy.
How to Prepare
- Ensure the sample is collected in the provided EDTA tube or FTA card.
- Label the sample with patient name and date of birth.
- For FTA card, allow the blood spot to air dry completely before sealing.
- Transport the sample to the lab within 24 hours if refrigerated.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"KIT gene mutations in AML are associated with poor prognosis and may influence treatment decisions. NGS testing provides comprehensive mutation profiling to guide targeted therapy."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Improperly labeled sample
- Sample received after prolonged delay without proper storage
Understanding Your Results
No KIT mutation detected
No pathogenic variants found in the KIT gene. This suggests a lower risk of relapse in AML subtypes, but other genetic factors may still be relevant.
KIT mutation detected (e.g., D816V)
Presence of a KIT mutation, often associated with poor prognosis in AML. May indicate potential benefit from tyrosine kinase inhibitors (e.g., midostaurin, dasatinib) and closer monitoring.
Variant of uncertain significance (VUS)
A genetic variant was found, but its clinical impact is not yet established. Further testing or family studies may be recommended.
Consult your oncologist or hematologist if you have been diagnosed with AML or if you experience symptoms such as persistent fatigue, recurrent infections, easy bruising, or unexplained weight loss. Genetic counseling is also recommended to understand the implications of test results.
Limitations
- ⚠This test detects mutations only in the KIT gene; other AML-related genes are not analyzed.
- ⚠Mutations in non-coding regions or large deletions may not be detected by NGS.
- ⚠Results should be interpreted in conjunction with clinical and cytogenetic findings.
- ⚠Not intended for screening healthy individuals without clinical suspicion.
Risks & Considerations
- ●Minimal risk of bruising or bleeding at the puncture site
- ●Rare risk of infection
- ●Psychological impact of receiving genetic results
Interfering Factors
- ●Insufficient DNA quantity or quality
- ●Contamination during sample collection
- ●Recent blood transfusion (may dilute patient cells)
- ●Presence of clonal hematopoiesis of indeterminate potential (CHIP)
Compare With Similar Tests
| Test | KIT Gene Leukemia, acute myeloid NGS Genetic Test | FLT3 Mutation Analysis | NPM1 Mutation Analysis | CEBPA Mutation Analysis | Myeloid Malignancy NGS Panel |
|---|---|---|---|---|---|
| Comparison | KIT Gene Leukemia, acute myeloid NGS Genetic Test |
Frequently Asked Questions
What is the KIT gene and how is it related to leukemia?
What are the symptoms of KIT gene leukemia?
How is KIT gene leukemia diagnosed?
What is the cost of the KIT gene NGS genetic test in India?
What sample is required for the KIT gene NGS test?
Is fasting required before the test?
How long does it take to get the results?
What does a positive KIT mutation result mean?
Can this test be done at home?
Is genetic counseling provided with the test?
Are there any risks associated with the test?
Is this test covered by insurance?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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