KRAS,NRAS Test
Short Name: KRAS/NRAS
Also known as: KRAS Mutation Test, NRAS Mutation Test, RAS Gene Testing
KRAS,NRAS Test test available at DNA Labs India for ₹18,000. Uses Sanger Sequencing on Tumor tissue samples. Results in 7-8 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of KRAS and NRAS gene testing is to identify mutations in these oncogenes, which are crucial for diagnosing cancer subtypes and guiding targeted therapy decisions. This test helps in personalizing treatment plans, especially for cancers like colorectal, lung, and pancreatic cancer, where KRAS/NRAS mutations may indicate resistance to certain therapies like EGFR inhibitors.
- Test Code
- 3067
- Price
- ₹18,000
- Sample Type
- Tumor tissue
- Result Time
- 7-8 days
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
A doctor's prescription is required for KRAS/NRAS testing. Prescription is not applicable for surgery, pregnancy cases, or individuals planning to travel abroad.
Method: Biopsy/Surgery
Laboratory Analysis
Sample collection involves obtaining tumor tissue through biopsy or surgical procedure, performed by a healthcare professional.
Report Delivery
The sample is preserved and sent to the laboratory for DNA extraction and sequencing.
Timeline: 7-8 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of KRAS and NRAS gene testing is to identify mutations in these oncogenes, which are crucial for diagnosing cancer subtypes and guiding targeted therapy decisions. This test helps in personalizing treatment plans, especially for cancers like colorectal, lung, and pancreatic cancer, where KRAS/NRAS mutations may indicate resistance to certain therapies like EGFR inhibitors.
How to Prepare
- Obtain tumor tissue via biopsy or surgery
- Ensure sample is properly labeled and transported in appropriate container
- Follow laboratory guidelines for sample handling
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample quantity
- Contaminated or hemolyzed sample
- Improper labeling or documentation
Understanding Your Results
Mutation detected
Presence of KRAS or NRAS mutation, which may affect response to targeted therapies like EGFR inhibitors. Consult oncologist for treatment adjustments.
No mutation detected
Wild-type KRAS and NRAS genes, suggesting potential responsiveness to certain targeted therapies. Clinical correlation is recommended.
Consult a doctor if you experience symptoms such as unexplained weight loss, abdominal pain, blood in stool, jaundice, difficulty breathing, or have a cancer diagnosis requiring treatment planning.
Limitations
- ⚠Test only detects mutations in KRAS and NRAS genes; other genetic alterations may not be identified
- ⚠Results may vary based on tumor heterogeneity
- ⚠Not suitable for germline mutation analysis
Risks & Considerations
- ●Risks associated with biopsy or surgery, such as infection, bleeding, or discomfort
- ●Minimal risk from genetic testing itself
Interfering Factors
- ●Contaminated or insufficient tumor sample
- ●Degraded DNA
- ●Previous treatments affecting tumor tissue
Frequently Asked Questions
What is KRAS and NRAS gene testing?
Why is KRAS/NRAS testing important for cancer treatment?
What sample is required for this test?
Is fasting required before the test?
How long does it take to get results?
Is home sample collection available?
What is the cost of KRAS/NRAS testing in India?
Who should undergo KRAS/NRAS testing?
What do the test results mean?
Are there any risks associated with the test?
Can this test be done without a doctor's prescription?
How accurate is KRAS/NRAS testing at DNA Labs India?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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