LARS2 Gene Hydrops, lactic acidosis, and sideroblastic anemia NGS Genetic Test
Short Name: LARS2 Gene Hydrops, Lactic Acidosis, Sideroblastic Anemia NGS Test
Also known as: LARS2 gene disorder, Hydrops-lactic acidosis-sideroblastic anemia syndrome
LARS2 Gene Hydrops, lactic acidosis, and sideroblastic anemia NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 3, 2026
Overview
To identify pathogenic mutations in the LARS2 gene for accurate diagnosis of hydrops, lactic acidosis, and sideroblastic anemia, facilitating early treatment and genetic counseling.
- Test Code
- 5593
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3-4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Provide clinical history and family pedigree during genetic counseling.
Method: Venipuncture
Laboratory Analysis
Blood sample collected via venipuncture by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site. Sample sent to laboratory for analysis.
Timeline: 3-4 weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify pathogenic mutations in the LARS2 gene for accurate diagnosis of hydrops, lactic acidosis, and sideroblastic anemia, facilitating early treatment and genetic counseling.
How to Prepare
- Ensure proper identification of patient
- Use sterile equipment
- Label sample correctly
- Transport at ambient temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for LARS2 mutations is crucial for families with a history of metabolic disorders, enabling timely intervention and informed reproductive decisions."
Last medically reviewed: September 3, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient volume
- Improper labeling
- Contaminated sample
Understanding Your Results
Positive for pathogenic variant
Confirms LARS2 gene mutation; recommend genetic counseling and clinical management.
Negative for pathogenic variant
No mutations detected; consider other genetic or metabolic causes.
Variant of uncertain significance
Further analysis and family studies may be needed.
If symptoms such as hydrops, lactic acidosis, anemia, developmental delays, or seizures are present, or if there is a family history of LARS2 mutations.
Limitations
- ⚠May not detect all genetic variants
- ⚠Requires genetic counseling for interpretation
- ⚠Not suitable for prenatal diagnosis without additional validation
Risks & Considerations
- ●Minimal risk from blood draw: bruising, infection, or discomfort
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Hemolyzed blood sample
Frequently Asked Questions
What is the LARS2 Gene NGS Genetic Test?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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