MDM2 Gene Accelerated tumor formation, susceptibility to NGS Genetic Test
Short Name: MDM2 NGS Genetic Test
Also known as: MDM2 gene mutation test, MDM2 cancer susceptibility test, MDM2 NGS analysis
MDM2 Gene Accelerated tumor formation, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify mutations in the MDM2 gene that increase susceptibility to accelerated tumor formation and cancer, facilitating early detection and personalized management strategies.
- Test Code
- 5557
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation required. Genetic counseling is recommended prior to testing to discuss implications and family history.
Method: Venipuncture or fingerstick
Laboratory Analysis
Standard blood draw procedure using sterile equipment. For FTA card, a single drop of blood is applied.
Report Delivery
Apply pressure to the puncture site to stop bleeding. Store samples as per instructions before transport.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the MDM2 gene that increase susceptibility to accelerated tumor formation and cancer, facilitating early detection and personalized management strategies.
How to Prepare
- Ensure proper patient identification and labeling
- Use sterile collection tubes or FTA cards
- Avoid hemolysis by gentle mixing
- Transport samples at ambient temperature unless specified
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for MDM2 mutations can guide preventive strategies and improve cancer outcomes, especially for individuals with a family history."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Improper labeling or documentation
- Contaminated or degraded samples
Understanding Your Results
Positive for Pathogenic Variant
Increased risk of accelerated tumor formation and cancer. Recommend genetic counseling, enhanced surveillance, and possible preventive measures.
Negative for Pathogenic Variant
No MDM2 mutations detected. However, cancer risk may still be present due to other genetic or environmental factors. Continue routine screening as advised.
Variant of Uncertain Significance (VUS)
Variant detected but clinical significance unknown. Further testing or family studies may be needed. Consult a genetic counselor for guidance.
Consult a healthcare provider or genetic counselor if results are positive, if there is a family history of cancer, or if symptoms persist. For negative results, discuss ongoing risk management with your doctor.
Limitations
- ⚠May not detect all types of MDM2 gene mutations, such as large deletions or duplications
- ⚠Results require interpretation by a genetic counselor or healthcare provider
- ⚠Does not replace clinical diagnosis or other cancer screening methods
- ⚠Genetic risk does not guarantee cancer development; environmental factors also play a role
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of results, including anxiety or stress
- ●Potential for insurance or discrimination issues, though protected by laws in some regions
Interfering Factors
- ●Sample contamination or degradation
- ●Insufficient DNA quantity or quality
- ●Recent blood transfusions or stem cell transplants
- ●Technical errors in sequencing or analysis
Compare With Similar Tests
| Test | MDM2 Gene Accelerated tumor formation, susceptibility to NGS Genetic Test | BRCA1/2 Gene Test | TP53 Gene Test | Comprehensive Cancer Panel | Somatic Tumor Testing |
|---|---|---|---|---|---|
| Comparison | MDM2 Gene Accelerated tumor formation, susceptibility to NGS Genetic Test | Focuses on breast and ovarian cancer risk; MDM2 test covers broader tumor susceptibility. | Associated with Li-Fraumeni syndrome; MDM2 test complements by assessing p53 pathway regulation. | Includes multiple genes; MDM2 test is specific for targeted analysis. | Analyzes tumor DNA; MDM2 germline test assesses inherited risk. |
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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