Microsatellite Instability (Lynch Syndrome/Colorectal Cancer) Test
Short Name: MSI Test
Also known as: Microsatellite Instability Test, Lynch Syndrome Screening Test
Microsatellite Instability (Lynch Syndrome/Colorectal Cancer) Test test available at DNA Labs India for ₹15,000. Uses Fragment Analysis on Tumor tissue & Peripheral Blood samples. Results in 7-8 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To detect microsatellite instability for the diagnosis of Lynch Syndrome and to assess the risk and treatment options for colorectal cancer.
- Test Code
- 3092
- Price
- ₹15,000
- Sample Type
- Tumor tissue & Peripheral Blood
- Result Time
- 7-8 days
- Fasting Required
- No
- Method
- Fragment Analysis
Sample Collection
A doctor's prescription is required. Prescription is not needed for surgery, pregnancy, or travel abroad cases.
Method: Venipuncture for blood; Biopsy for tissue
Laboratory Analysis
Standard blood draw or biopsy procedure.
Report Delivery
Apply pressure to the puncture site for blood draw; follow biopsy care instructions.
Timeline: 7-8 days
Patient Instructions
About This Test
Who Should Get This Test
To detect microsatellite instability for the diagnosis of Lynch Syndrome and to assess the risk and treatment options for colorectal cancer.
How to Prepare
- For blood: Ensure proper venipuncture technique
- For tissue: Collect biopsy sample in paraffin block
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"MSI testing is essential for diagnosing Lynch Syndrome and assessing colorectal cancer risk, guiding personalized treatment plans."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood sample
- Insufficient tissue quantity
Understanding Your Results
MSI-High
Indicates high instability, suggestive of Lynch Syndrome or sporadic MSI-High colorectal cancer. Further genetic counseling recommended.
MSI-Low
Low instability, lower risk for Lynch Syndrome but may require monitoring.
MSS
Microsatellite stable, no evidence of instability, reducing likelihood of Lynch Syndrome.
If you experience symptoms of colorectal cancer, have a family history of Lynch Syndrome, or if your test results indicate MSI-High.
Limitations
- ⚠Test may not detect all Lynch Syndrome cases
- ⚠Requires sufficient tumor tissue
Risks & Considerations
- ●Minor bruising from blood draw
- ●Infection or bleeding from biopsy
- ●Discomfort during procedure
Interfering Factors
- ●Poor sample quality
- ●Contamination
- ●Inadequate tissue sample
Frequently Asked Questions
What is Microsatellite Instability (MSI) testing?
Why is MSI testing important for Lynch Syndrome?
What are the symptoms of Lynch Syndrome and colorectal cancer?
How is MSI testing performed?
What is the cost of MSI testing in India?
Is MSI testing covered by insurance?
How long does it take to get MSI test results?
What does an MSI-High result mean?
Can MSI testing be done at home?
What is the difference between MSI and other genetic tests?
Who should get MSI testing?
How accurate is MSI testing?
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Reference Laboratory Services
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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