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MLL t(4;11)(q21;q23) Qualitative Test

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MLL t(4;11)(q21;q23) Qualitative Test

Short Name: MLL t(4;11) Qualitative

Also known as: MLL translocation t(4;11), AF4-MLL fusion, MLL-AF4 translocation

MLL t(4;11)(q21;q23) Qualitative Test test available at DNA Labs India for ₹4,500. Uses Real Time PCR on Bone marrow / Peripheral blood samples. Results in 3-4 days. Free home collection in 300+ cities across India.

Genetic Test🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the MLL t(4;11)(q21;q23) qualitative test is to detect the presence of the chromosomal translocation between chromosomes 4 and 11, which is a genetic marker for certain leukemias. This test assists in diagnosis, prognosis assessment, and guiding targeted treatment strategies.

Test Code
3117
Price
₹4,500
Sample Type
Bone marrow / Peripheral blood
Result Time
3-4 days
Fasting Required
No
Method
Real Time PCR
Step 1

Sample Collection

A doctor's prescription is required. Prescription is not applicable for surgery, pregnancy cases, or people planning to travel abroad.

Method: Bone marrow aspiration or venipuncture

Step 2

Laboratory Analysis

Sample is collected via bone marrow aspiration or venipuncture into an EDTA vacutainer (2 ml).

Step 3

Report Delivery

Transport the sample immediately to the laboratory with a cool pack to maintain stability during transit.

Timeline: 3-4 days

Patient Instructions

1
Before the Test:Obtain a doctor's prescription and inform the healthcare provider about any medications, medical conditions, or recent procedures.
2
During the Test:Sample collection is performed by a trained professional following standard protocols for bone marrow or blood draw.
3
After the Test:Wait for 3-4 days for report delivery via online portal, email, or WhatsApp.

About This Test

Who Should Get This Test

The purpose of the MLL t(4;11)(q21;q23) qualitative test is to detect the presence of the chromosomal translocation between chromosomes 4 and 11, which is a genetic marker for certain leukemias. This test assists in diagnosis, prognosis assessment, and guiding targeted treatment strategies.

How to Prepare

  • Use EDTA vacutainer (2 ml)
  • Transport immediately with cool pack
  • Ensure proper labeling and documentation

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Early detection of MLL t(4;11) translocation is crucial for personalized treatment and improved outcomes in leukemia patients."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBone marrow / Peripheral blood
Sample Volume2 ml
ContainerEDTA Vacutainer
Collection MethodBone marrow aspiration or venipuncture

Sample Stability

Stable for 24 hours at 2-8°C
Avoid freezing or exposure to extreme temperatures
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Improper container or insufficient volume
  • Delayed transport beyond stability period

Understanding Your Results

Results are reported qualitatively as Detected or Not Detected for the MLL t(4;11) translocation.
📊

Detected

Presence of MLL t(4;11) translocation, indicating a genetic abnormality associated with leukemia. Immediate consultation with an oncologist or hematologist is recommended for further management.

📊

Not Detected

No MLL t(4;11) translocation detected. Clinical correlation with symptoms and other diagnostic tests is advised.

⚠️ When to Consult a Doctor:

If symptoms of leukemia persist, if the test result is positive, or if there is a family history of genetic disorders, consult a hematologist or oncologist promptly.

Limitations

  • Qualitative test only; does not provide quantitative data
  • May not detect all variants of MLL gene rearrangements
  • Requires adequate sample quality and volume

Risks & Considerations

  • Minor bruising or pain at the collection site
  • Rare risk of infection
  • Discomfort during bone marrow aspiration

Interfering Factors

  • Sample contamination
  • Improper sample storage or transport
  • Hemolyzed or clotted samples

Frequently Asked Questions

What is MLL t(4;11)(q21;q23)?
MLL t(4;11)(q21;q23) is a chromosomal translocation between chromosomes 4 and 11, resulting in a fusion gene that is associated with certain types of leukemia.
Why is the MLL t(4;11) qualitative test done?
This test is done to detect the presence of the MLL t(4;11) translocation, which helps in diagnosing leukemia, assessing prognosis, and guiding treatment decisions.
How is the test performed?
The test uses Real Time PCR technology on a bone marrow or peripheral blood sample to qualitatively detect the translocation.
What is the cost of the MLL t(4;11) qualitative test at DNA Labs India?
The test costs INR 4500, with free home sample collection available across India.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
How long does it take to get the test results?
Results are typically available within 3-4 days after sample collection.
What does a positive test result mean?
A positive result indicates the presence of the MLL t(4;11) translocation, suggesting a genetic abnormality linked to leukemia. Consult an oncologist for further evaluation.
What does a negative test result mean?
A negative result means the translocation was not detected. Clinical correlation with symptoms and other tests is recommended.
Are there any risks associated with the test?
Risks are minimal and may include minor bruising, pain at the collection site, or rare infection. Bone marrow aspiration may cause temporary discomfort.
Do I need a doctor's prescription for this test?
Yes, a doctor's prescription is required, except for surgery, pregnancy cases, or people planning to travel abroad.
What sample type is required for the test?
The test requires a bone marrow or peripheral blood sample collected in an EDTA vacutainer (2 ml).
How should I prepare for the test?
No special preparation is needed, but ensure you have a valid prescription and follow collection instructions provided by the lab.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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