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Myelin Associated Glycoprotein-Sulfated Glucuronic Paragloboside Autoantibody (MAG-SGPG) IgM Test

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Myelin Associated Glycoprotein-Sulfated Glucuronic Paragloboside Autoantibody (MAG-SGPG) IgM Test

Short Name: MAG-SGPG IgM Antibody Test

Also known as: MAG Antibody Test, SGPG Antibody Test, MAG-SGPG IgM Test, Anti-MAG/SGPG Test

Myelin Associated Glycoprotein-Sulfated Glucuronic Paragloboside Autoantibody (MAG-SGPG) IgM Test test available at DNA Labs India for ₹14,000. Uses EIA, Endpoint Titer on Serum samples. Results in Reports are typically available within 2-3 weeks after sample receipt.. Free home collection in 300+ cities across India.

Autoantibody Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To detect MAG-SGPG IgM autoantibodies for diagnosing autoimmune neurological conditions such as demyelinating neuropathies and related disorders.

Test Code
1277
Price
₹14,000
Sample Type
Serum
Result Time
Reports are typically available within 2-3 weeks after sample receipt.
Fasting Required
Yes (8 hours)
Method
EIA, Endpoint Titer
Step 1

Sample Collection

Overnight fasting is preferred. Ensure the Test Send Out Consent Form (Form 35) is duly filled and available.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in the arm using standard venipuncture technique.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Resume normal activities unless advised otherwise.

Timeline: Reports are typically available within 2-3 weeks after sample receipt.

Patient Instructions

1
Before the Test:Overnight fasting is preferred. Complete the Test Send Out Consent Form (Form 35) and bring it to the collection center.
2
During the Test:A healthcare professional will collect a blood sample from your arm vein.
3
After the Test:You may experience minor bruising at the puncture site. Results will be available online after 2-3 weeks.

About This Test

Who Should Get This Test

To detect MAG-SGPG IgM autoantibodies for diagnosing autoimmune neurological conditions such as demyelinating neuropathies and related disorders.

How to Prepare

  • Overnight fasting is preferred
  • Duly filled Test Send Out Consent Form (Form 35) is mandatory
  • Sample must be collected in an SST tube
  • Ship refrigerated or frozen as per stability guidelines

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test is essential for diagnosing autoimmune neuropathies and guiding targeted treatment plans."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerator (2-8°C): 14 days
Frozen (-20°C): 30 days
Sample Rejection Criteria:
  • Incorrect sample type or container
  • Insufficient sample volume (less than 1 mL)
  • Hemolyzed or contaminated samples
  • Missing consent form

Understanding Your Results

The MAG-SGPG IgM test result helps in diagnosing autoimmune neuropathies. Positive results indicate the presence of antibodies targeting nerve cells, while negative results suggest their absence.
Negative: No detectable MAG-SGPG IgM antibodies. May not support diagnosis of associated conditions.
Positive: Presence of MAG-SGPG IgM antibodies. Correlates with demyelinating neuropathies like CIDP or MGUS.
Equivocal: Borderline results; retesting or additional tests may be recommended.
High Titer: Often associated with more severe demyelination and clinical symptoms.
⚠️ When to Consult a Doctor:

Consult a doctor if test results are positive or equivocal, or if you experience symptoms like weakness, numbness, or difficulty walking. A healthcare provider can guide further evaluation and treatment.

Limitations

  • ⚠May yield false positives in certain conditions like monoclonal gammopathies
  • ⚠Not specific for all types of neuropathies
  • ⚠Results should be correlated with clinical findings and other tests

Risks & Considerations

  • ●Minor pain or bruising at the blood draw site
  • ●Rare risk of infection or dizziness
  • ●No significant risks associated with the test itself

Interfering Factors

  • ●Hemolyzed or lipemic samples
  • ●Recent infections or vaccinations
  • ●Immunosuppressive therapy

Compare With Similar Tests

TestMyelin Associated Glycoprotein-Sulfated Glucuronic Paragloboside Autoantibody (MAG-SGPG) IgM TestAnti-MAG Antibody TestNerve Conduction Study (NCS)Serum Protein Electrophoresis (SPEP)
ComparisonMyelin Associated Glycoprotein-Sulfated Glucuronic Paragloboside Autoantibody (MAG-SGPG) IgM TestSimilar to MAG-SGPG but focuses solely on MAG antibodies. MAG-SGPG test includes SGPG for broader detection.NCS assesses nerve function electrically, while MAG-SGPG detects underlying autoimmune causes.SPEP identifies monoclonal proteins, which may be associated with MAG-SGPG positive conditions.

Frequently Asked Questions

What is the MAG-SGPG IgM test?
It is a blood test that detects IgM antibodies against myelin-associated glycoprotein and sulfated glucuronic paragloboside, used to diagnose autoimmune neuropathies.
Why is this test recommended?
It is recommended for symptoms like numbness, weakness, or tingling in limbs, and to diagnose conditions such as CIDP or MGUS.
What is the cost of the test at DNA Labs India?
The test costs INR 14,000, including free home sample collection across India.
How is the sample collected?
A blood sample is drawn from a vein in the arm. Overnight fasting is preferred, and a consent form is required.
What are the symptoms that indicate this test?
Symptoms include weakness, numbness, tingling, difficulty walking, loss of reflexes, fatigue, and pain in arms or legs.
What conditions can this test diagnose?
It helps diagnose Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Monoclonal Gammopathy of Undetermined Significance (MGUS), Waldenström's Macroglobulinemia, and Multiple Myeloma.
Is fasting required for this test?
Yes, overnight fasting is preferred for accurate results.
How long does it take to get the results?
Results are typically available within 2-3 weeks after sample receipt.
Is home collection available?
Yes, DNA Labs India offers free home sample collection for this test across India.
What does a positive result mean?
A positive result indicates the presence of MAG-SGPG IgM antibodies, suggesting an autoimmune attack on peripheral nerves, which may be associated with neuropathic conditions.
Can this test be done for children?
The test is applicable for all ages, but consultation with a healthcare provider is recommended for pediatric cases.
What is the significance of a high titer MAG-SGPG IgM result?
A high titer indicates a stronger immune response against nerve cells, often associated with more severe demyelination and clinical symptoms. It may guide treatment decisions.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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