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Myelin Basic Protein MBP Test

DNA Labs India | ISO 9001:2015 Certified

Myelin Basic Protein MBP Test

Short Name: MBP Test

Also known as: Myelin Basic Protein Assay, MBP CSF Test

Myelin Basic Protein MBP Test test available at DNA Labs India for ₹10,000. Uses Radioimmunoassay (RIA) on Cerebrospinal Fluid (CSF) samples. Results in 2-3 weeks. Free home collection in 300+ cities across India.

Immunology Test🏠 Home Collection

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Overview

The MBP test is performed to measure levels of myelin basic protein in CSF or blood, indicating damage to the myelin sheath. It aids in diagnosing demyelinating diseases, monitoring disease activity, and guiding treatment plans for neurological conditions.

Test Code
1275
Price
₹10,000
Sample Type
Cerebrospinal Fluid (CSF)
Result Time
2-3 weeks
Fasting Required
Yes (4 hours)
Method
Radioimmunoassay (RIA)
Step 1

Sample Collection

Fast for 4-6 hours before the test. Ensure the Test Send Out Consent Form (Form 35) is duly filled and available.

Method: Lumbar Puncture

Step 2

Laboratory Analysis

CSF sample is collected via lumbar puncture, typically from the 4th lumbar puncture tube to minimize blood contamination.

Step 3

Report Delivery

Rest for a few hours post-procedure. Monitor for any side effects like headache or back pain.

Timeline: 2-3 weeks

Patient Instructions

1
Before the Test:Fast for 4-6 hours. Complete necessary paperwork, including consent forms.
2
During the Test:CSF sample collection via lumbar puncture, which may cause mild discomfort.
3
After the Test:Rest and hydrate. Report any severe headaches or neurological symptoms to your doctor.

About This Test

Who Should Get This Test

The MBP test is performed to measure levels of myelin basic protein in CSF or blood, indicating damage to the myelin sheath. It aids in diagnosing demyelinating diseases, monitoring disease activity, and guiding treatment plans for neurological conditions.

How to Prepare

  • Submit 2 mL of CSF in a sterile screw capped container.
  • Do not centrifuge the sample.
  • Ship the sample refrigerated or frozen.
  • Ensure no blood contamination or hemolysis.
  • Duly filled Test Send Out Consent Form (Form 35) is mandatory.

Doctor's Notes

"The MBP test is crucial for early detection of demyelinating diseases, aiding timely intervention and management to improve patient outcomes."

Test Parameters & Specifications

Sample TypeCerebrospinal Fluid (CSF)
Sample Volume2 mL (1 mL min.)
ContainerSterile screw capped container
Collection MethodLumbar Puncture

Sample Stability

Room Temperature6 hours
Refrigerator14 days
Frozen21 days
Sample Rejection Criteria:
  • Sample with blood contamination
  • Hemolyzed CSF sample
  • Incorrect or insufficient sample volume
  • Missing consent form

Understanding Your Results

Interpretation of MBP test results involves comparing levels to reference ranges and considering clinical context.
📊

Suggests demyelination or neuronal damage, common in MS, NMO, ADEM, head injury, stroke, or viral encephalitis.

Level: Elevated (≥4 ng/mL)

📊

Indicates no significant demyelination, but symptoms may require further evaluation.

Level: Normal (<4 ng/mL)

⚠️ When to Consult a Doctor:

Consult a doctor if MBP levels are elevated or if symptoms like numbness, weakness, or vision changes persist or worsen.

Limitations

  • ⚠MBP levels may rise in conditions beyond demyelinating diseases, such as head injury or viral encephalitis.
  • ⚠Test results should be correlated with clinical findings and other diagnostics.
  • ⚠Reference ranges may vary between laboratories.

Risks & Considerations

  • ●Post-lumbar puncture headache
  • ●Back pain or soreness at puncture site
  • ●Rare risk of infection or bleeding

Interfering Factors

  • ●Blood contamination in CSF sample
  • ●Hemolysis during sample collection
  • ●Improper sample storage or handling

Compare With Similar Tests

TestMyelin Basic Protein MBP TestOligoclonal Bands TestMRI Brain
ComparisonMyelin Basic Protein MBP TestDetects immune activity in CSF, often used alongside MBP for MS diagnosis.Imaging test to visualize demyelination in the brain and spinal cord.

Frequently Asked Questions

What is the Myelin Basic Protein (MBP) test?
The MBP test measures levels of myelin basic protein in CSF or blood to detect damage to the myelin sheath, aiding in diagnosis of neurological disorders.
Why is the MBP test important?
It helps in early detection of demyelinating diseases like multiple sclerosis, enabling timely treatment and management.
What symptoms indicate the need for an MBP test?
Symptoms include numbness, limb weakness, walking difficulties, blurred vision, fatigue, and speech problems.
How is the MBP test performed?
A CSF sample is collected via lumbar puncture or a blood sample is drawn, then analyzed in a lab using radioimmunoassay.
What is the cost of the MBP test in India?
The cost is approximately INR 10,000, with home sample collection available in many cities.
Is fasting required before the MBP test?
Yes, patients are typically asked to fast for 4-6 hours before the test.
What are the risks of the MBP test?
Risks are minimal but may include headache, back pain, or rare infection from lumbar puncture.
How long does it take to get MBP test results?
Results are usually available within 2-3 weeks after sample collection.
What do elevated MBP levels indicate?
Elevated levels suggest demyelination, which can occur in conditions like MS, head injury, stroke, or viral encephalitis.
Can the MBP test be done at home?
Yes, DNA Labs India offers free home sample collection for this test in various cities.
What should I do if my MBP test results are abnormal?
Consult a neurologist or immunologist for further evaluation and potential treatment options.
Is the MBP test covered by insurance in India?
Coverage varies; check with your insurance provider or schemes like PMJAY for eligibility.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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