Myeloproliferative Leukemia Mutation Screening (MPL - S505N; W515L) Test
Short Name: MPL Mutation Screening
Also known as: MPL Gene Mutation Test, MPL S505N W515L Screening
Myeloproliferative Leukemia Mutation Screening (MPL - S505N; W515L) Test test available at DNA Labs India for ₹6,750. Uses Sanger Sequencing on Bone Marrow/Peripheral Blood samples. Results in 5-7 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect specific mutations in the MPL gene, namely S505N and W515L, which are associated with myeloproliferative leukemia. Identifying these mutations aids in accurate diagnosis, prognosis assessment, and treatment planning.
- Test Code
- 3102
- Price
- ₹6,750
- Sample Type
- Bone Marrow/Peripheral Blood
- Result Time
- 5-7 days
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
Myeloproliferative Leukemia Mutation Screening (MPL - S505N; W515L) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Method: Venipuncture for blood, Bone Marrow Aspiration for bone marrow
Laboratory Analysis
Sample collection involves drawing blood via venipuncture or performing a bone marrow aspiration, depending on the sample type required.
Report Delivery
A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.
Timeline: 5-7 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect specific mutations in the MPL gene, namely S505N and W515L, which are associated with myeloproliferative leukemia. Identifying these mutations aids in accurate diagnosis, prognosis assessment, and treatment planning.
How to Prepare
- Obtain a doctor's prescription if required.
- Inform the healthcare provider about any medications or conditions.
- Follow standard preparation for blood draw or bone marrow biopsy.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This genetic test is essential for detecting MPL mutations, which are key in diagnosing myeloproliferative neoplasms and guiding treatment decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Understanding Your Results
Consult a doctor if you experience symptoms like fatigue, weight loss, or enlarged spleen, or if test results are positive for mutations.
Risks & Considerations
- ●For blood sample: Minor bruising or discomfort at the puncture site.
- ●For bone marrow biopsy: Risk of infection, bleeding, or pain at the aspiration site.
Frequently Asked Questions
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