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DNA Labs India

NGS TP53 Mutation Analysis Test

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NGS TP53 Mutation Analysis Test

NGS TP53 Mutation Analysis Test test available at DNA Labs India for ₹40,000. Uses Next-Generation Sequencing (NGS) on Bone marrow / Peripheral blood samples. Results in 15-18 days. Free home collection in 300+ cities across India.

Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of NGS TP53 Mutation Analysis is to identify pathogenic variants in the TP53 gene that may indicate a hereditary cancer syndrome. This information is crucial for early detection, risk assessment, and management of cancer-prone individuals.

Test Code
3109
Price
₹40,000
Sample Type
Bone marrow / Peripheral blood
Result Time
15-18 days
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

A doctor's prescription is required for this test. Prescription is not applicable for surgery, pregnancy cases, or individuals planning to travel abroad.

Method: Venipuncture

Step 2

Laboratory Analysis

Your sample is analyzed using Next-Generation Sequencing (NGS) in our laboratory.

Step 3

Report Delivery

A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.

Timeline: 15-18 days

Patient Instructions

1
Before the Test:A doctor's prescription is required for this test. Prescription is not applicable for surgery, pregnancy cases, or individuals planning to travel abroad.

About This Test

Who Should Get This Test

The purpose of NGS TP53 Mutation Analysis is to identify pathogenic variants in the TP53 gene that may indicate a hereditary cancer syndrome. This information is crucial for early detection, risk assessment, and management of cancer-prone individuals.

How to Prepare

  • Sample must be transported immediately after collection.
  • Use EDTA Vacutainer (2ml) for blood sample.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBone marrow / Peripheral blood
Sample Volume2ml
ContainerEDTA Vacutainer
Collection MethodVenipuncture

Understanding Your Results

Results of the NGS TP53 Mutation Analysis should be interpreted by a qualified genetic counselor or healthcare provider. A positive result indicates the presence of a pathogenic variant in the TP53 gene, which may increase the risk of developing certain cancers.
Positive Result: Pathogenic variant detected. Consult with a genetic counselor for risk assessment and management options.
Negative Result: No pathogenic variant detected. However, this does not eliminate cancer risk entirely.
Variant of Uncertain Significance (VUS): Further evaluation may be needed.
⚠️ When to Consult a Doctor:

If you have a family history of cancer, experience symptoms associated with TP53 mutations, or receive a positive test result, consult a genetic counselor or oncologist for personalized advice.

Risks & Considerations

  • ●Minimal physical risk from blood draw.
  • ●Potential psychological impact from test results.

Frequently Asked Questions

What is NGS TP53 Mutation Analysis?
NGS TP53 Mutation Analysis is a genetic test that uses next-generation sequencing to identify mutations in the TP53 gene, which is associated with hereditary cancer syndromes like Li-Fraumeni syndrome.
Why is this test recommended?
This test is recommended for individuals with a family history of cancer, early-onset cancers, multiple primary cancers, or symptoms linked to TP53 mutations to assess genetic risk.
How is the test performed?
The test is performed using a blood or bone marrow sample collected in an EDTA Vacutainer. The DNA is analyzed via next-generation sequencing to detect TP53 gene mutations.
What is the cost of the test?
The cost of NGS TP53 Mutation Analysis at DNA Labs India is INR 40000, which includes the genetic test and genetic counseling fees.
Is home collection available?
Yes, free home sample collection is available for online bookings across many cities in India, including Mumbai, Delhi, Bangalore, and others.
How long does it take to get results?
The turnaround time for NGS TP53 Mutation Analysis is 15-18 days. Reports are delivered via online portal, email, or WhatsApp.
What does a positive result mean?
A positive result indicates the presence of a pathogenic variant in the TP53 gene, which may increase the risk of developing certain cancers. Consult a genetic counselor for further guidance.
What does a negative result mean?
A negative result means no pathogenic variant was detected in the TP53 gene. However, it does not eliminate cancer risk entirely, as other factors may be involved.
Is genetic counseling included?
Yes, the test cost includes consultation with a genetic counselor to help interpret the results and provide personalized risk assessment.
Who should consider this test?
Individuals with a family history of cancer, those diagnosed with cancer at a young age, or people with multiple cancer types should consider this test.
Are there any risks associated with the test?
The test involves minimal physical risks from blood draw. There may be psychological impacts from test results, which are addressed through genetic counseling.
How can I book the test?
You can book the test online through DNA Labs India's website or by calling the provided number. Free home collection is available for online bookings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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