NPM1+FLT3 Test
Also known as: NPM1 and FLT3 Mutation Test, AML Genetic Testing
NPM1+FLT3 Test test available at DNA Labs India for ₹12,000. Uses Sanger Sequencing on Bone marrow or Peripheral blood samples. Results in 7-8 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To detect mutations in NPM1 and FLT3 genes for diagnosis, prognosis assessment, and treatment planning in Acute Myeloid Leukemia (AML).
- Test Code
- 3118
- Price
- ₹12,000
- Sample Type
- Bone marrow or Peripheral blood
- Result Time
- 7-8 days
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
Consult with your doctor for prescription. No specific preparation required.
Method: Venipuncture for blood, Bone marrow aspiration for bone marrow
Laboratory Analysis
Sample will be collected by a trained phlebotomist or pathologist.
Report Delivery
Apply pressure to the collection site to prevent bleeding.
Timeline: 7-8 days
Patient Instructions
About This Test
Who Should Get This Test
To detect mutations in NPM1 and FLT3 genes for diagnosis, prognosis assessment, and treatment planning in Acute Myeloid Leukemia (AML).
How to Prepare
- Ensure sample is transported immediately
- Use EDTA vacutainer
- Label sample correctly
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"NPM1 and FLT3 mutations are crucial for prognosis in AML. This test aids in personalized treatment planning, improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient sample volume
- Incorrect container
Understanding Your Results
NPM1 Mutation Positive
Associated with better prognosis in AML and may guide treatment decisions.
FLT3 Mutation Positive
May indicate poorer prognosis and suggest targeted therapy options.
Both Mutations Negative
Standard prognosis; other factors should be considered for treatment planning.
If you have symptoms of AML such as fatigue, shortness of breath, or easy bruising, or have been diagnosed with AML, consult your doctor for this test.
Limitations
- ⚠Test only detects specific mutations in NPM1 and FLT3 genes
- ⚠May not detect all genetic variants
- ⚠Results should be interpreted in clinical context
Risks & Considerations
- ●Minor bruising at collection site
- ●Infection risk (rare)
- ●Discomfort during bone marrow aspiration
Interfering Factors
- ●Sample contamination
- ●Improper sample handling
- ●Recent blood transfusion
Compare With Similar Tests
| Test | NPM1+FLT3 | FLT3-ITD Test | NPM1 Mutation Test | AML Comprehensive Panel | Bone Marrow Biopsy |
|---|---|---|---|---|---|
| Comparison | NPM1+FLT3 | Focuses only on FLT3 mutations, not NPM1. | Focuses only on NPM1 mutations, not FLT3. | Includes multiple genes beyond NPM1 and FLT3. | Provides morphological assessment, not genetic details. |
Frequently Asked Questions
What is the NPM1+FLT3 test?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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