Oligoclonal Bands IgG CSF & Serum Test
Short Name: Oligoclonal Bands Test
Also known as: CSF Oligoclonal Bands Test, IgG Oligoclonal Bands Analysis
Oligoclonal Bands IgG CSF & Serum Test test available at DNA Labs India for ₹7,000. Uses Isoelectrofocusing, Immunoturbidimetry, Nephelometry on CSF and Serum samples. Results in Report delivered next day after sample receipt by 9 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
To detect oligoclonal bands in CSF and serum samples, aiding in the diagnosis of multiple sclerosis and other autoimmune or inflammatory conditions affecting the central nervous system.
- Test Code
- 1353
- Price
- ₹7,000
- Sample Type
- CSF and Serum
- Result Time
- Report delivered next day after sample receipt by 9 am.
- Fasting Required
- No
- Method
- Isoelectrofocusing, Immunoturbidimetry, Nephelometry
Sample Collection
Ensure serum and CSF samples are collected simultaneously for accurate comparison. Inform the healthcare provider about any medications or recent procedures.
Method: Lumbar puncture for CSF, venipuncture for serum
Laboratory Analysis
CSF is collected via lumbar puncture, and serum is obtained through venipuncture. The process is performed by trained medical professionals.
Report Delivery
Serum should be separated from blood within one hour of collection. Both samples must be shipped refrigerated but not frozen to maintain stability.
Timeline: Report delivered next day after sample receipt by 9 am.
Patient Instructions
About This Test
Who Should Get This Test
To detect oligoclonal bands in CSF and serum samples, aiding in the diagnosis of multiple sclerosis and other autoimmune or inflammatory conditions affecting the central nervous system.
How to Prepare
- Collect 2 mL CSF in a sterile screw capped container
- Collect 2 mL serum from a Serum Separator Tube (SST)
- Separate serum within 1 hour of collection
- Ship samples refrigerated, do not freeze
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This test is vital for confirming multiple sclerosis when clinical symptoms are present. Results should always be interpreted alongside neurological exams and imaging studies like MRI for accurate diagnosis."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Samples that are hemolyzed, lipemic, or improperly stored
- Insufficient sample volume
- Unlabeled or contaminated containers
Understanding Your Results
Positive
Oligoclonal bands detected in CSF, indicating intrathecal IgG synthesis. This is supportive of multiple sclerosis but can occur in other autoimmune conditions.
Negative
No oligoclonal bands detected. Makes multiple sclerosis less likely, though early disease may show negative results.
If you experience symptoms like numbness, vision problems, or balance issues, or if test results are positive, consult a neurologist for comprehensive evaluation and management.
Limitations
- ⚠False positives can occur in conditions like subacute sclerosing panencephalitis, inflammatory polyneuropathy, CNS lupus, or brain tumors
- ⚠Does not differentiate between active and inactive disease stages
- ⚠Results must be correlated with clinical and radiological findings
Risks & Considerations
- ●Lumbar puncture may cause headache, back pain, or rarely, infection
- ●Venipuncture risks include minor bruising or discomfort
Interfering Factors
- ●Hemolyzed or lipemic samples
- ●Improper sample storage or handling
- ●Recent infections or immunizations may affect results
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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