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DNA Labs India

Oncomine Tumor Mutation Burden (TMB) Test

DNA Labs India | ISO 9001:2015 Certified

Oncomine Tumor Mutation Burden (TMB) Test

Also known as: TMB Test, Tumor Mutation Burden Test

Oncomine Tumor Mutation Burden (TMB) Test test available at DNA Labs India for ₹62,000. Uses Next-Generation Sequencing (NGS) on Tumor tissue samples. Results in 2-3 weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS)Adults🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the Oncomine TMB test is to predict the response of cancer patients to immunotherapy by quantifying the number of mutations in tumor DNA, helping in treatment selection and personalized therapy.

Test Code
3130
Price
₹62,000
Sample Type
Tumor tissue
Result Time
2-3 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Oncomine Tumor Mutation Burden (TMB) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Method: Biopsy or Surgical Tissue

Step 2

Laboratory Analysis

Sample is collected via biopsy or surgery to obtain tumor tissue.

Step 3

Report Delivery

Tissue sample is preserved and sent to the laboratory for DNA extraction and sequencing.

Timeline: 2-3 weeks

Patient Instructions

1
Before the Test:Obtain a doctor's prescription and schedule sample collection.
2
During the Test:Tumor tissue sample is collected and processed in the laboratory using NGS.
3
After the Test:Results are analyzed and reported; follow up with your physician for interpretation.

About This Test

Who Should Get This Test

The purpose of the Oncomine TMB test is to predict the response of cancer patients to immunotherapy by quantifying the number of mutations in tumor DNA, helping in treatment selection and personalized therapy.

How to Prepare

  • Obtain tumor tissue through biopsy or surgical procedure
  • Ensure sample is properly labeled and preserved
  • Transport sample to laboratory under appropriate conditions

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"TMB testing is crucial for personalizing immunotherapy in cancer care, helping identify patients who may benefit from immune checkpoint inhibitors."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue
Collection MethodBiopsy or Surgical Tissue

Understanding Your Results

Results are reported as mutations per megabase (mut/Mb). Higher TMB may indicate a better response to immunotherapy, but interpretation should be done by a qualified oncologist.
High TMB (e.g., >10 mut/Mb) is often associated with improved response to immunotherapy
Low TMB may suggest lower likelihood of benefit from immune checkpoint inhibitors
Results should be correlated with cancer type, stage, and other biomarkers
Consult with an oncologist for personalized treatment decisions based on TMB
⚠️ When to Consult a Doctor:

Consult your oncologist to discuss TMB results and implications for immunotherapy or other treatment options.

Limitations

  • TMB is a biomarker and may not be definitive for all cancer types
  • Results should be interpreted in conjunction with other clinical and pathological findings
  • Test accuracy depends on sample quality and tumor heterogeneity

Risks & Considerations

  • Risks associated with biopsy or surgery, such as infection, bleeding, or discomfort
  • Potential for inconclusive results due to sample quality

Frequently Asked Questions

What is the Oncomine Tumor Mutation Burden (TMB) test?
The Oncomine TMB test is a genetic test that measures the number of mutations in tumor DNA to predict response to immunotherapy in cancer patients.
How is the Oncomine TMB test performed?
The test uses Next-Generation Sequencing (NGS) technology on a tumor tissue sample collected via biopsy or surgery to analyze mutations.
What is the cost of the Oncomine TMB test in India?
The cost is INR 62000 at DNA Labs India, with free home sample collection available across India.
Who should consider taking the Oncomine TMB test?
Cancer patients, especially those with advanced or metastatic cancers, who are considering immunotherapy or personalized treatment.
What are the benefits of the Oncomine TMB test?
It helps predict immunotherapy response, aids in treatment selection, and provides accurate assessment of tumor mutational burden.
How long does it take to get results for the Oncomine TMB test?
Results are typically available in 2-3 weeks after sample collection.
Is home sample collection available for the Oncomine TMB test?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
What sample is required for the Oncomine TMB test?
A tumor tissue sample obtained through biopsy or surgery is required.
Is fasting required before the Oncomine TMB test?
No, fasting is not required for this test.
How accurate is the Oncomine TMB test?
The test uses advanced NGS technology for accurate detection, but results should be interpreted in clinical context.
What does a high TMB result mean?
A high TMB (e.g., >10 mutations per megabase) may indicate a better response to immunotherapy, but consultation with an oncologist is essential.
Can the Oncomine TMB test replace other biomarkers?
It complements other biomarkers and should be used alongside clinical evaluation for comprehensive treatment planning.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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