PDGFR + cKIT (Gastrointestinal Stromal Tumors) Test
Short Name: PDGFR + cKIT GIST Test
Also known as: GIST Mutation Test, PDGFR and cKIT Gene Analysis
PDGFR + cKIT (Gastrointestinal Stromal Tumors) Test test available at DNA Labs India for ₹15,000. Uses Sanger Sequencing on Tumor tissue samples. Results in 7-8 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of PDGFR + cKIT testing is to identify mutations in the PDGFR and cKIT genes associated with Gastrointestinal Stromal Tumors. This information is essential for confirming diagnosis, assessing tumor aggressiveness, and determining eligibility for targeted therapies such as imatinib.
- Test Code
- 3138
- Price
- ₹15,000
- Sample Type
- Tumor tissue
- Result Time
- 7-8 days
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
Obtain doctor's prescription. Ensure proper biopsy procedure and sample handling.
Method: Biopsy
Laboratory Analysis
Tissue sample collected via biopsy under sterile conditions by a qualified professional.
Report Delivery
Sample preserved and transported to the laboratory for analysis at ambient temperature.
Timeline: 7-8 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of PDGFR + cKIT testing is to identify mutations in the PDGFR and cKIT genes associated with Gastrointestinal Stromal Tumors. This information is essential for confirming diagnosis, assessing tumor aggressiveness, and determining eligibility for targeted therapies such as imatinib.
How to Prepare
- Use sterile equipment
- Label sample correctly with patient details
- Transport at ambient temperature within 24 hours
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early detection through PDGFR and cKIT testing can significantly improve treatment outcomes for GIST patients by guiding targeted therapy."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate sample size
- Improper labeling
- Contaminated or degraded sample
Understanding Your Results
Mutation Detected
Confirms GIST diagnosis and may guide targeted therapy with drugs like imatinib.
No Mutation Detected
GIST less likely, but clinical correlation with imaging and histopathology is recommended.
If symptoms persist or worsen, or if test results are abnormal, consult an oncologist or genetic specialist for further evaluation and management.
Limitations
- ⚠May not detect all mutations
- ⚠Requires adequate tumor sample
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Minimal risk from biopsy procedure
- ●Possible infection or bleeding at biopsy site
- ●Rare allergic reaction to anesthesia
Interfering Factors
- ●Poor sample quality
- ●Insufficient tumor tissue
- ●Contamination
Compare With Similar Tests
| Test | PDGFR + cKIT (Gastrointestinal Stromal Tumors) | Immunohistochemistry (IHC) for cKIT | CT Scan for Abdomen |
|---|---|---|---|
| Comparison | PDGFR + cKIT (Gastrointestinal Stromal Tumors) | IHC detects protein expression, while genetic testing identifies specific mutations for targeted therapy. | Imaging tests like CT scan visualize tumor location and size, but genetic testing confirms molecular characteristics. |
Frequently Asked Questions
What is PDGFR + cKIT testing?
Why is this test important for GIST diagnosis?
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What sample is required?
Is fasting required for this test?
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What is the cost of the test?
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Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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