PIK3CA by NGS Test
Also known as: PIK3CA Mutation Testing, PIK3CA Gene Sequencing
PIK3CA by NGS Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Peripheral blood samples. Results in 10-15 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the PIK3CA by NGS test is to identify mutations in the PIK3CA gene, which are associated with various cancers. This information aids in diagnosis, prognosis, and selection of targeted therapies, such as PI3K inhibitors, for cancer patients.
- Test Code
- 3153
- Price
- ₹20,000
- Sample Type
- Peripheral blood
- Result Time
- 10-15 days
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Ensure a doctor's prescription is available if needed.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities.
Timeline: 10-15 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the PIK3CA by NGS test is to identify mutations in the PIK3CA gene, which are associated with various cancers. This information aids in diagnosis, prognosis, and selection of targeted therapies, such as PI3K inhibitors, for cancer patients.
How to Prepare
- Bring a valid ID and doctor's prescription
- Wear loose clothing for easy access to the arm
- Stay hydrated before the test
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"PIK3CA testing is essential for identifying targeted therapy options in cancer treatment, improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Incorrect sample type or container
Understanding Your Results
Negative
No PIK3CA mutation detected. Standard treatment protocols may be followed.
Positive
PIK3CA mutation detected. Consider targeted therapies such as PI3K inhibitors. Consult with an oncologist for personalized treatment.
Consult your doctor immediately after receiving results to discuss implications and treatment options, especially if positive.
Limitations
- ⚠Cannot detect all possible mutations in the PIK3CA gene
- ⚠Results may be affected by tumor heterogeneity
- ⚠Requires confirmation with additional testing in some cases
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Rare risk of infection or excessive bleeding
Interfering Factors
- ●Poor sample quality or insufficient DNA
- ●Contamination during sample collection or processing
- ●Use of certain medications that may affect DNA integrity
Compare With Similar Tests
| Test | PIK3CA by NGS | BRCA1/2 Testing | EGFR Mutation Testing | KRAS Testing |
|---|---|---|---|---|
| Comparison | PIK3CA by NGS | Focuses on hereditary breast and ovarian cancer genes, while PIK3CA testing targets somatic mutations in various cancers. | Relevant for lung cancer, whereas PIK3CA is broader across cancer types. | Common in colorectal cancer, PIK3CA testing complements it for comprehensive profiling. |
Frequently Asked Questions
What is PIK3CA by NGS?
What is the cost of PIK3CA by NGS in India?
What are the symptoms of PIK3CA mutations?
How is the test performed?
Is fasting required for this test?
How long does it take to get results?
What does a positive result mean?
Is home collection available?
Do I need a doctor's prescription?
What cancers are associated with PIK3CA mutations?
How accurate is the NGS-based testing?
What should I do after receiving results?
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Reference Laboratory Services
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