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DNA Labs India

PIK3CA Gene Cowden syndrome type 5 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

PIK3CA Gene Cowden syndrome type 5 NGS Genetic Test

Also known as: Cowden Syndrome Type 5 Genetic Test, PIK3CA Mutation Analysis, Hereditary Cancer Syndrome Test

PIK3CA Gene Cowden syndrome type 5 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To diagnose Cowden Syndrome Type 5 by detecting mutations in the PIK3CA gene using Next-Generation Sequencing technology, aiding in early identification and management of associated cancer risks.

Test Code
2860
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS
Step 1

Sample Collection

Provide detailed clinical history of the patient and undergo a genetic counseling session to draw a pedigree chart of family members affected with Cowden Syndrome Type 5.

Step 2

Laboratory Analysis

Your sample is analyzed using NGS in our laboratory.

Step 3

Report Delivery

A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling to draw a family pedigree chart.
2
During the Test:A blood sample or extracted DNA will be collected for analysis using NGS technology.
3
After the Test:Results will be available in 3 to 4 weeks. Discuss findings with a healthcare provider for appropriate follow-up.

About This Test

Who Should Get This Test

To diagnose Cowden Syndrome Type 5 by detecting mutations in the PIK3CA gene using Next-Generation Sequencing technology, aiding in early identification and management of associated cancer risks.

How to Prepare

  • Ensure proper patient identification and documentation.
  • Blood sample will be collected by a trained phlebotomist using standard venipuncture.
  • For FTA card collection, follow specific instructions for applying one drop of blood.
  • Maintain sample integrity during transport to the laboratory.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for PIK3CA mutations is crucial for diagnosing Cowden Syndrome Type 5, enabling proactive cancer surveillance and management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Understanding Your Results

Results from the PIK3CA Gene Cowden Syndrome Type 5 NGS Genetic Test indicate the presence or absence of mutations in the PIK3CA gene, which are associated with Cowden Syndrome Type 5 and increased cancer risk.
📊

Positive for pathogenic PIK3CA mutation

Diagnosis of Cowden Syndrome Type 5 is likely. Consult a genetic counselor and oncologist for personalized cancer surveillance and management plans.

📊

Negative for pathogenic PIK3CA mutation

No mutation detected. Clinical correlation is recommended; symptoms may be due to other causes. Consider repeat testing if clinical suspicion remains high.

📊

Variant of uncertain significance (VUS)

A genetic variant was found but its clinical significance is unknown. Further testing and family studies may be needed. Genetic counseling is advised.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms such as persistent skin lesions, thyroid abnormalities, breast lumps, gastrointestinal polyps, or neurological issues, or if you have a family history of Cowden Syndrome or related cancers.

Risks & Considerations

  • ●Minor pain or bruising at the blood draw site
  • ●Rare risk of infection or hematoma
  • ●Psychological impact of genetic results; counseling recommended

Frequently Asked Questions

What is Cowden Syndrome Type 5?
Cowden Syndrome Type 5 is a rare genetic disorder caused by mutations in the PIK3CA gene, leading to an increased risk of developing tumors and cancers in various organs.
What causes Cowden Syndrome Type 5?
It is caused by pathogenic mutations in the PIK3CA gene, which is involved in cell growth and division. These mutations are usually inherited in an autosomal dominant pattern.
What are the common symptoms of Cowden Syndrome Type 5?
Symptoms include skin abnormalities (e.g., warts, skin tags), thyroid issues (e.g., nodules), breast lumps, gastrointestinal polyps, and brain abnormalities like seizures or developmental delays.
How is Cowden Syndrome Type 5 diagnosed?
Diagnosis involves clinical evaluation and genetic testing, such as the PIK3CA Gene NGS Genetic Test, to identify mutations in the PIK3CA gene.
What is the cost of the PIK3CA Gene Cowden Syndrome Type 5 NGS Genetic Test?
The test costs INR 20,000 at DNA Labs India, with free home sample collection available across India.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
How long does it take to get the test results?
Results are typically delivered within 3 to 4 weeks after sample collection.
Is the genetic test accurate?
Yes, NGS technology provides high accuracy in detecting mutations in the PIK3CA gene, but results should be interpreted in clinical context.
Can this test be performed on children?
Yes, the test can be performed on individuals of all ages, but genetic counseling is recommended for minors and their families.
What should I do if the test result is positive?
A positive result indicates a mutation associated with Cowden Syndrome Type 5. Consult a genetic counselor and oncologist for personalized cancer surveillance and management.
Is genetic counseling required before testing?
Yes, genetic counseling is recommended before and after testing to understand the implications, family risks, and interpretation of results.
How can I book the PIK3CA Gene Cowden Syndrome Type 5 NGS Genetic Test?
You can book the test online through DNA Labs India's website or contact their customer service for assistance with home collection or walk-in options.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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