PIK3CA Mutation Analysis (Exon 7, 9 & 20) Test
Short Name: PIK3CA Mutation Analysis
Also known as: PIK3CA Gene Mutation Test, PIK3CA Genetic Analysis
PIK3CA Mutation Analysis (Exon 7, 9 & 20) Test test available at DNA Labs India for ₹9,000. Uses Sanger Sequencing on Tumor Tissue samples. Results in 7-8 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of PIK3CA Mutation Analysis is to identify genetic mutations in the PIK3CA gene that may indicate an elevated risk for developing cancers such as breast, ovarian, and colorectal cancer. This test aids in diagnosis, prognosis, and treatment planning by providing actionable genetic information.
- Test Code
- 3149
- Price
- ₹9,000
- Sample Type
- Tumor Tissue
- Result Time
- 7-8 days
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
Ensure a doctor's prescription is available. Inform the healthcare provider about any medications or medical conditions. No specific fasting is required.
Method: Tissue Sample Collection
Laboratory Analysis
A tumor tissue sample will be collected, typically via biopsy or from paraffin-embedded tissue blocks. The procedure is performed by a trained professional.
Report Delivery
Apply pressure to the collection site if needed. Follow any post-procedure instructions from the healthcare provider. The sample will be sent to the lab for analysis.
Timeline: 7-8 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of PIK3CA Mutation Analysis is to identify genetic mutations in the PIK3CA gene that may indicate an elevated risk for developing cancers such as breast, ovarian, and colorectal cancer. This test aids in diagnosis, prognosis, and treatment planning by providing actionable genetic information.
How to Prepare
- Obtain a doctor's prescription for the test
- Use sterile equipment for sample collection
- Label the sample correctly with patient details
- Transport the sample in appropriate conditions as specified
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"PIK3CA mutation analysis is crucial for identifying cancer risk and guiding personalized treatment decisions, especially in breast, ovarian, and colorectal cancers."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Contaminated or degraded sample
- Missing patient identification or prescription
- Sample not collected according to guidelines
Understanding Your Results
Mutation Detected
Indicates a PIK3CA mutation in exon 7, 9, or 20, which may be associated with higher cancer risk or influence treatment options like targeted therapies.
No Mutation Detected
No mutations found in the tested exons; however, this does not rule out mutations in other genes or exons.
Consult a doctor if you have a family history of cancer, experience symptoms like unexplained weight loss or fatigue, or if results indicate a mutation. Discuss implications for treatment and screening.
Limitations
- ⚠This test only analyzes exons 7, 9, and 20 of the PIK3CA gene; other mutations may not be detected
- ⚠Results may not be conclusive for all cancer types
- ⚠Genetic testing has limitations in predicting disease onset or severity
- ⚠False negatives or positives can occur due to technical issues
Risks & Considerations
- ●Minimal risk from sample collection, such as minor bleeding or infection
- ●Psychological impact from genetic results
- ●Potential for inconclusive results requiring further testing
Interfering Factors
- ●Poor sample quality or insufficient tissue
- ●Contamination during sample collection or processing
- ●Use of certain medications that may affect DNA integrity
- ●Improper storage or handling of the sample
Compare With Similar Tests
| Test | PIK3CA Mutation Analysis (Exon 7, 9 & 20) | BRCA1/2 Mutation Analysis | EGFR Mutation Analysis |
|---|---|---|---|
| Comparison | PIK3CA Mutation Analysis (Exon 7, 9 & 20) | Focuses on BRCA genes linked to breast and ovarian cancer, while PIK3CA targets a different gene pathway. | Detects mutations in the EGFR gene, often for lung cancer, whereas PIK3CA is more relevant for breast, ovarian, and colorectal cancers. |
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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