PML/RARA Qualitative [BCR 1 & 3] Test
Also known as: PML-RARA Fusion Gene Test, APL Diagnostic Test
PML/RARA Qualitative [BCR 1 & 3] Test test available at DNA Labs India for ₹5,250. Uses Real Time PCR on Bone marrow / Peripheral blood samples. Results in 2-3 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
To detect the PML/RARA fusion gene for diagnosing Acute Promyelocytic Leukemia (APL).
- Test Code
- 3151
- Price
- ₹5,250
- Sample Type
- Bone marrow / Peripheral blood
- Result Time
- 2-3 days
- Fasting Required
- No
- Method
- Real Time PCR
Sample Collection
A doctor's prescription may be required. Prescription is not applicable for surgery, pregnancy, or travel abroad cases.
Method: Venipuncture or bone marrow aspiration
Laboratory Analysis
Sample is collected via venipuncture for peripheral blood or bone marrow aspiration.
Report Delivery
Transport the sample immediately with a cool pack to maintain integrity.
Timeline: 2-3 days
Patient Instructions
About This Test
Who Should Get This Test
To detect the PML/RARA fusion gene for diagnosing Acute Promyelocytic Leukemia (APL).
How to Prepare
- Use EDTA vacutainer for blood collection
- Transport sample immediately
- Maintain cool chain during transport
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This test is essential for confirming APL diagnosis and initiating targeted therapy promptly."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Incorrect sample type
- Insufficient volume
Understanding Your Results
Detected
Positive for PML/RARA fusion gene, consistent with APL diagnosis.
Not Detected
Negative for PML/RARA fusion gene; APL is unlikely, but clinical correlation is advised.
If the test is positive or symptoms persist, consult an oncologist or hematologist immediately.
Limitations
- ⚠Qualitative test only; does not quantify gene expression
- ⚠May have false negatives in early stages
- ⚠Requires confirmatory testing in some cases
Risks & Considerations
- ●Minor pain or bruising at blood draw site
- ●Risk of infection from bone marrow aspiration (rare)
Interfering Factors
- ●Sample contamination
- ●Improper storage
- ●Hemolyzed sample
Compare With Similar Tests
| Test | PML/RARA Qualitative [BCR 1 & 3] | Cytogenetic Analysis | FISH for PML/RARA | Flow Cytometry |
|---|---|---|---|---|
| Comparison | PML/RARA Qualitative [BCR 1 & 3] | Detects chromosomal abnormalities but may take longer. | Fluorescence in situ hybridization for specific gene detection. | Used for immunophenotyping of leukemia cells. |
Frequently Asked Questions
What is the PML/RARA Qualitative [BCR 1 & 3] test?
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