POLE Gene FILS syndrome NGS Genetic Test
Short Name: POLE Gene FILS Syndrome NGS Test
Also known as: POLE Gene Mutation Test, FILS Syndrome Genetic Test, POLE NGS Test
POLE Gene FILS syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS, Next-Generation Sequencing on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify mutations in the POLE gene for diagnosing POLE Gene FILS Syndrome, assessing cancer risk, and guiding preventive measures and family screening.
- Test Code
- 5743
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks from sample receipt.
- Fasting Required
- No
- Method
- NGS, Next-Generation Sequencing
Sample Collection
Genetic counseling session recommended to discuss test implications and obtain informed consent.
Method: Venipuncture or FTA card collection
Laboratory Analysis
Blood sample drawn by a trained phlebotomist using aseptic techniques.
Report Delivery
Sample is labeled, stored, and transported to the laboratory for analysis.
Timeline: 3 to 4 weeks from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the POLE gene for diagnosing POLE Gene FILS Syndrome, assessing cancer risk, and guiding preventive measures and family screening.
How to Prepare
- Ensure proper sample labeling with patient details
- Follow aseptic techniques to avoid contamination
- Use appropriate collection tubes or FTA cards
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for POLE mutations can guide cancer prevention strategies and family screening, especially for individuals with a history of FILS Syndrome or related cancers."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Improper labeling or storage
Understanding Your Results
Mutation detected
Increased risk for POLE Gene FILS Syndrome and associated cancers. Consult a genetic counselor for further guidance and screening.
Action: Regular cancer screening and preventive measures recommended.
No mutation detected
Lower risk for POLE Gene FILS Syndrome, but standard cancer screening should continue based on age and family history.
Action: Follow general health guidelines and consult healthcare provider if symptoms arise.
If you have symptoms of cancer, a family history of FILS Syndrome, or early-onset cancers, consult a healthcare provider or genetic counselor to discuss testing.
Limitations
- ⚠May not detect all genetic variants
- ⚠Requires genetic counseling for interpretation
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of results, requiring counseling support
Interfering Factors
- ●Sample degradation
- ●Contamination
- ●Improper sample handling
Compare With Similar Tests
| Test | POLE Gene FILS syndrome NGS Genetic Test | BRCA1/2 Gene Test | Lynch Syndrome Panel |
|---|---|---|---|
| Comparison | POLE Gene FILS syndrome NGS Genetic Test |
Frequently Asked Questions
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