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DNA Labs India

Predictive Genetic Testing for Cancer Test

DNA Labs India | ISO 9001:2015 Certified

Predictive Genetic Testing for Cancer Test

Short Name: PGTC

Also known as: Hereditary Cancer Panel, Cancer Risk Assessment Test, Genetic Cancer Screening

Predictive Genetic Testing for Cancer Test test available at DNA Labs India for ₹18,000. Uses Next-Generation Sequencing (NGS), Sanger Sequencing for confirmation on Blood samples. Results in Results are typically available within 10-14 business days after the sample reaches the laboratory.. Free home collection in 300+ cities across India.

Molecular / GenomicAdult🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

The purpose of predictive genetic testing for cancer is to identify inherited genetic mutations that increase an individual's risk of developing certain types of cancer. This test is not diagnostic but predictive, helping individuals understand their genetic predisposition and take proactive steps for prevention, early detection, and risk management. It enables personalized surveillance plans, preventive measures, and informed family planning decisions.

Test Code
6455
CPT Code
81432
ICD Code
Z13.9
Price
₹18,000
Sample Type
Blood
Result Time
Results are typically available within 10-14 business days after the sample reaches the laboratory.
Fasting Required
No
Method
Next-Generation Sequencing (NGS), Sanger Sequencing for confirmation
Step 1

Sample Collection

No special preparation is required. However, inform your healthcare provider about any medications or supplements you are taking. Avoid blood transfusion for at least 2 weeks prior to the test.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be collected from a vein in your arm. The procedure is quick and minimally invasive.

Step 3

Report Delivery

You may resume normal activities immediately. There are no restrictions after sample collection.

Timeline: Results are typically available within 10-14 business days after the sample reaches the laboratory.

Patient Instructions

1
Before the Test:Before the test, you will have a pre-test genetic counseling session to understand the implications, benefits, and limitations. You may also be asked to provide a detailed family history.
2
During the Test:During the test, a blood sample is collected. The procedure is quick and usually takes less than 5 minutes.
3
After the Test:After the test, you will receive your results in 10-14 days. A post-test counseling session will be scheduled to explain the results and discuss next steps.

About This Test

Who Should Get This Test

The purpose of predictive genetic testing for cancer is to identify inherited genetic mutations that increase an individual's risk of developing certain types of cancer. This test is not diagnostic but predictive, helping individuals understand their genetic predisposition and take proactive steps for prevention, early detection, and risk management. It enables personalized surveillance plans, preventive measures, and informed family planning decisions.

How to Prepare

  • No fasting required
  • Hydrate well before sample collection
  • Inform the phlebotomist if you have a bleeding disorder or are on anticoagulants
  • Ensure the sample is collected in the provided EDTA tube

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Predictive genetic testing is a cornerstone of precision oncology. Identifying high-risk individuals allows for early surveillance and preventive strategies, significantly reducing cancer mortality."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood
Sample Volume5 mL
ContainerEDTA (purple top) tube
Collection MethodVenipuncture

Sample Stability

Whole blood: 24 hours at 2-8°C
Extracted DNA: 1 week at -20°C
Avoid repeated freeze-thaw cycles
Sample Rejection Criteria:
  • Clotted sample
  • Hemolyzed sample
  • Incorrect tube used
  • Sample received after 48 hours without proper storage

Understanding Your Results

The interpretation of predictive genetic testing results is based on the presence or absence of pathogenic variants in the analyzed genes. Results are classified as Positive, Negative, or Variant of Uncertain Significance (VUS).
📊

Positive (Pathogenic variant detected)

Increased risk for associated cancers. Clinical action plan recommended, including enhanced surveillance and preventive measures.

📊

Negative (No pathogenic variant detected)

No increased hereditary risk identified. General cancer prevention guidelines apply.

📊

Variant of Uncertain Significance (VUS)

A genetic change was found, but its impact on cancer risk is unknown. Further family studies may be needed.

⚠️ When to Consult a Doctor:

Consult your healthcare provider if you have a family history of cancer, if you have been diagnosed with cancer at a young age, or if you are considering predictive testing. Also, consult if you receive a positive or VUS result to discuss next steps.

Limitations

  • ⚠Only detects mutations in the genes included in the panel; other genetic causes may not be identified
  • ⚠Variant of Uncertain Significance (VUS) results may not provide clear clinical guidance
  • ⚠Negative result does not eliminate cancer risk entirely; environmental and lifestyle factors still play a role
  • ⚠Test is predictive, not diagnostic; it does not confirm the presence of cancer

Risks & Considerations

  • ●Psychological impact of learning about increased cancer risk
  • ●Potential for genetic discrimination (though HIPAA-compliant privacy is ensured)
  • ●Variant of Uncertain Significance may cause anxiety
  • ●False reassurance if negative result (still need regular screenings)

Interfering Factors

  • ●Recent blood transfusion (within 2 weeks) may dilute DNA
  • ●Bone marrow transplantation can affect results
  • ●Clotted or hemolyzed samples may cause test failure
  • ●Certain medications (e.g., immunosuppressants) may affect DNA quality

Compare With Similar Tests

TestPredictive Genetic Testing for CancerCarcinoembryonic Antigen (CEA)CA-125MammographyColonoscopy
ComparisonPredictive Genetic Testing for Cancer

Frequently Asked Questions

What is predictive genetic testing for cancer?
Predictive genetic testing for cancer identifies inherited mutations in genes that increase the risk of developing certain cancers. It is not a diagnostic test but a risk assessment tool.
Who should consider this test?
Individuals with a family history of cancer, early-onset cancer, multiple cancers in the family, or those planning proactive health management should consider this test.
What genes are included in the panel?
The panel includes 50+ genes such as BRCA1, BRCA2, TP53, ATM, CHEK2, MLH1, APC, RET, CDH1, and PALB2, among others.
How is the test performed?
A blood sample is collected from your arm. The DNA is extracted and analyzed using next-generation sequencing (NGS) for >99.9% accuracy.
Do I need to fast before the test?
No, fasting is not required for this test.
How long does it take to get results?
Results are typically available within 10-14 business days after the sample reaches the laboratory.
What does a positive result mean?
A positive result indicates the presence of a pathogenic variant associated with increased cancer risk. You will receive a clinical action plan and counseling.
What does a negative result mean?
A negative result means no pathogenic variants were detected in the analyzed genes. However, it does not eliminate cancer risk entirely.
What is a Variant of Uncertain Significance (VUS)?
A VUS is a genetic change whose impact on cancer risk is unknown. Further family studies may be needed to clarify its significance.
Is genetic counseling included?
Yes, free pre- and post-test tele-genetic counseling is included with the test.
Is home sample collection available?
Yes, free home sample collection is available across India, including in Hayathnagar, Madhapur, and Amberpet.
How much does the test cost?
The test costs ?18,000, which includes the gene panel, counseling, and sample collection. This is a discounted price for 2025.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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