RAD50 Gene Hereditary breast and ovarian cancer syndrome, RAD50 related NGS Genetic Test
Short Name: RAD50 NGS Genetic Test
Also known as: RAD50 Gene Test, HBOC RAD50 Test, RAD50 Mutation Analysis
RAD50 Gene Hereditary breast and ovarian cancer syndrome, RAD50 related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically available within 3 to 4 weeks after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the RAD50 Gene NGS Genetic Test is to detect mutations in the RAD50 gene that are linked to hereditary breast and ovarian cancer syndrome (HBOC). This test helps in assessing an individual's genetic risk for developing breast and ovarian cancers, enabling early intervention, personalized screening plans, and informed decision-making for patients and their families.
- Test Code
- 2875
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Results are typically available within 3 to 4 weeks after sample collection.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Genetic counseling is recommended before sample collection to discuss test implications, benefits, and limitations.
Method: Venipuncture or FTA card spotting
Laboratory Analysis
A blood sample is collected via venipuncture, or a DNA sample is provided via FTA card. Ensure proper labeling and aseptic techniques.
Report Delivery
The sample is sent to the laboratory for DNA extraction and NGS analysis. Results are typically available in 3 to 4 weeks.
Timeline: Results are typically available within 3 to 4 weeks after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the RAD50 Gene NGS Genetic Test is to detect mutations in the RAD50 gene that are linked to hereditary breast and ovarian cancer syndrome (HBOC). This test helps in assessing an individual's genetic risk for developing breast and ovarian cancers, enabling early intervention, personalized screening plans, and informed decision-making for patients and their families.
How to Prepare
- Ensure patient identification and sample labeling
- Use sterile collection equipment
- Follow standard phlebotomy procedures
- For FTA cards, apply one drop of blood and air-dry
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for RAD50 mutations is crucial for early detection and personalized management of hereditary breast and ovarian cancer syndrome, enabling proactive risk-reduction strategies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Contaminated or improperly labeled samples
Understanding Your Results
Positive
A pathogenic variant in the RAD50 gene was detected, indicating an increased risk for breast and ovarian cancer. Further screening and risk-reduction strategies are recommended.
Negative
No pathogenic variant was detected in the RAD50 gene. However, this does not eliminate all genetic risks, and clinical correlation is advised.
Variant of Uncertain Significance (VUS)
A genetic variant was found, but its clinical significance is unclear. Additional testing and genetic counseling may be needed.
Consult a doctor if you experience symptoms of breast or ovarian cancer, have a family history of HBOC, or receive a positive or VUS result from this test.
Limitations
- ⚠Test only detects known mutations in the RAD50 gene
- ⚠Does not rule out other genetic causes of HBOC
- ⚠Results require interpretation by a genetic counselor or healthcare provider
- ⚠May not detect all types of genetic variations
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Potential psychological impact of results, including anxiety or stress
- ●Risk of false positives or negatives, though rare with NGS technology
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Improper sample storage or handling
Compare With Similar Tests
| Test | RAD50 Gene Hereditary breast and ovarian cancer syndrome, RAD50 related NGS Genetic Test | BRCA1 Gene Test | BRCA2 Gene Test | PALB2 Gene Test | Multi-Gene Panel Test |
|---|---|---|---|---|---|
| Comparison | RAD50 Gene Hereditary breast and ovarian cancer syndrome, RAD50 related NGS Genetic Test |
Frequently Asked Questions
What is the RAD50 gene test?
Who should consider getting this test?
How is the test performed?
What does a positive result mean?
What does a negative result mean?
Is genetic counseling required before testing?
What is the cost of the RAD50 gene test?
Is home sample collection available?
How long does it take to get results?
Are there any risks associated with the test?
Can this test detect all mutations in the RAD50 gene?
What should I do after receiving the results?
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