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RAD51D Gene Breast-ovarian cancer, familial, susceptibility to, type 4 NGS Genetic Test

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RAD51D Gene Breast-ovarian cancer, familial, susceptibility to, type 4 NGS Genetic Test

Short Name: RAD51D Gene Test

Also known as: RAD51D Mutation Test, RAD51D Gene Mutation Analysis

RAD51D Gene Breast-ovarian cancer, familial, susceptibility to, type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To detect mutations in the RAD51D gene that increase susceptibility to breast and ovarian cancer, enabling early risk assessment and personalized preventive care.

Test Code
2842
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Ensure genetic counseling is scheduled.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collected via venipuncture by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Resume normal activities.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling to discuss family history and test implications.
2
During the Test:Blood sample collection; procedure takes about 10-15 minutes.
3
After the Test:Results available in 3-4 weeks; follow-up counseling recommended.

About This Test

Who Should Get This Test

To detect mutations in the RAD51D gene that increase susceptibility to breast and ovarian cancer, enabling early risk assessment and personalized preventive care.

How to Prepare

  • Use sterile equipment for blood collection
  • Label samples correctly with patient details
  • Transport samples at ambient temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for RAD51D mutations is crucial for individuals with a family history of breast or ovarian cancer, enabling personalized risk assessment and preventive strategies."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5ml Blood
ContainerEDTA Tube
Collection MethodVenipuncture

Sample Stability

Blood samples stable for 7 days at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Incorrectly labeled samples
  • Insufficient sample volume

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the RAD51D gene. A positive result suggests increased cancer risk, while a negative result does not eliminate risk entirely.
Positive: Pathogenic variant detected; increased risk for breast and ovarian cancer. Consult a genetic counselor for management options.
Negative: No pathogenic variant detected; risk may be similar to general population, but family history should be considered.
Variant of Uncertain Significance (VUS): Further testing or family studies may be needed.
⚠️ When to Consult a Doctor:

Consult a doctor or genetic counselor if you have a family history of breast or ovarian cancer, receive a positive test result, or experience symptoms suggestive of cancer.

Limitations

  • ⚠May not detect all types of RAD51D mutations
  • ⚠Results require interpretation by a genetic counselor
  • ⚠Does not rule out other genetic or environmental risk factors

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Psychological impact of test results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA quality
  • ●Insufficient sample volume

Compare With Similar Tests

TestRAD51D Gene Breast-ovarian cancer, familial, susceptibility to, type 4 NGS Genetic TestBRCA1 Gene TestBRCA2 Gene TestPALB2 Gene TestATM Gene Test
ComparisonRAD51D Gene Breast-ovarian cancer, familial, susceptibility to, type 4 NGS Genetic Test

Frequently Asked Questions

What is the RAD51D gene?
The RAD51D gene is part of the RAD51 family involved in DNA repair. Mutations can increase the risk of breast and ovarian cancer.
Who should consider the RAD51D gene test?
Individuals with a family history of breast or ovarian cancer, or those with symptoms like abnormal bleeding or abdominal pain.
How is the test performed?
The test uses Next-Generation Sequencing (NGS) to analyze DNA from a blood sample or extracted DNA.
What does a positive result mean?
A positive result indicates a pathogenic variant in RAD51D, increasing the risk of breast and ovarian cancer. Genetic counseling is recommended.
What are the risks of the test?
Risks are minimal, primarily related to blood draw, such as bruising. Psychological impact may occur.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is the test covered by insurance?
Coverage varies by insurance plan. Check with your provider for details.
Can I get home sample collection?
Yes, DNA Labs India offers free home sample collection for this test across India.
What is the cost of the RAD51D gene test?
The test costs INR 20,000, inclusive of sample collection and report generation.
How accurate is the test?
The test is highly accurate using NGS technology, but results should be interpreted by a genetic counselor.
What should I do if I have a mutation?
Consult a healthcare provider for personalized risk management, which may include enhanced screening or preventive measures.
Is genetic counseling required before testing?
Yes, genetic counseling is recommended to understand the implications of testing and results.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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