RNASEL Gene Prostate cancer, hereditary type 1 NGS Genetic Test
Short Name: RNASEL Gene Test
Also known as: RNASEL Mutation Analysis, Hereditary Prostate Cancer Genetic Screening
RNASEL Gene Prostate cancer, hereditary type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect mutations in the RNASEL gene, specifically the R462Q mutation, which is associated with hereditary type 1 prostate cancer. It helps in assessing genetic risk, guiding screening strategies, and informing treatment decisions.
- Test Code
- 2941
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation required. Inform the lab about any medications or recent blood transfusions.
Method: Venipuncture or Saliva Collection
Laboratory Analysis
A small blood sample will be drawn from a vein in your arm, or a saliva sample will be collected.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect mutations in the RNASEL gene, specifically the R462Q mutation, which is associated with hereditary type 1 prostate cancer. It helps in assessing genetic risk, guiding screening strategies, and informing treatment decisions.
How to Prepare
- Fast for 8-12 hours if required, but for this test, fasting is not necessary
- Bring a valid ID and prescription
- Wear loose clothing for easy blood draw
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Genetic testing for RNASEL mutations is crucial for identifying individuals at high risk of hereditary prostate cancer, enabling proactive management and early intervention."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Incorrectly labeled samples
Understanding Your Results
Positive for R462Q mutation
Increased risk of hereditary prostate cancer. Recommend genetic counseling and regular screenings.
Negative for R462Q mutation
No detected mutation in the tested gene. Risk may still exist due to other factors.
If you have a family history of prostate cancer, experience symptoms, or receive a positive genetic test result, consult a healthcare provider for further evaluation and management.
Limitations
- ⚠This test only detects specific mutations in the RNASEL gene
- ⚠Results should be interpreted in conjunction with clinical findings and family history
- ⚠Does not rule out other genetic causes of prostate cancer
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of genetic results
Interfering Factors
- ●Contaminated DNA sample
- ●Improper sample storage
- ●Technical errors in sequencing
Compare With Similar Tests
| Test | RNASEL Gene Prostate cancer, hereditary type 1 NGS Genetic Test | PSA Blood Test | Digital Rectal Exam | Prostate Biopsy |
|---|---|---|---|---|
| Comparison | RNASEL Gene Prostate cancer, hereditary type 1 NGS Genetic Test | Measures prostate-specific antigen levels, not genetic mutations. | Physical examination of the prostate, not genetic. | Invasive procedure to detect cancer cells, not genetic risk. |
Frequently Asked Questions
What is the RNASEL Gene Prostate Cancer Test?
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