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DNA Labs India

RUNX1 Gene Leukemia, acute myeloid NGS Genetic Test

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RUNX1 Gene Leukemia, acute myeloid NGS Genetic Test

Short Name: RUNX1 AML NGS Test

Also known as: RUNX1-associated AML, RUNX1 mutation leukemia

RUNX1 Gene Leukemia, acute myeloid NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To identify mutations in the RUNX1 gene for diagnosis and personalized treatment of acute myeloid leukemia.

Test Code
2884
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation required. Provide clinical history and undergo genetic counseling if needed.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

Blood sample will be drawn by a trained phlebotomist using sterile equipment.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Sample will be processed in the laboratory.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Consult with a genetic counselor or oncologist to discuss test implications and provide clinical history.
2
During the Test:Sample collection via blood draw or FTA card, followed by laboratory processing using NGS technology.
3
After the Test:Report generation within 3-4 weeks, with results available online or via email/WhatsApp. Follow-up consultation recommended.

About This Test

Who Should Get This Test

To identify mutations in the RUNX1 gene for diagnosis and personalized treatment of acute myeloid leukemia.

How to Prepare

  • Use sterile collection tubes
  • Label samples with patient details
  • Transport at ambient room temperature
  • Avoid hemolysis during blood draw

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Early genetic testing for RUNX1 mutations can guide personalized treatment in acute myeloid leukemia, improving patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA Card

Sample Stability

Blood: 24 hours at room temperature
Extracted DNA: Stable for several days if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Incorrect labeling or missing information

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the RUNX1 gene, which are associated with acute myeloid leukemia.
📊

Positive

Pathogenic variant detected in RUNX1 gene, associated with increased risk of AML. Consult oncologist for treatment options.

📊

Negative

No pathogenic variants detected. Clinical correlation recommended if symptoms persist.

📊

Variant of Uncertain Significance

Genetic variant found but significance unclear. Further testing or family studies may be needed.

⚠️ When to Consult a Doctor:

If symptoms of leukemia persist, if genetic counseling is needed, or if results indicate a pathogenic variant.

Limitations

  • ⚠May not detect all RUNX1 mutations
  • ⚠Results require clinical correlation
  • ⚠Not suitable for prenatal diagnosis

Risks & Considerations

  • ●Minor bruising at puncture site
  • ●Rare risk of infection
  • ●Emotional impact of results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA quality
  • ●Previous treatments affecting DNA integrity

Compare With Similar Tests

TestRUNX1 Gene Leukemia, acute myeloid NGS Genetic TestSanger SequencingFISH Analysis
ComparisonRUNX1 Gene Leukemia, acute myeloid NGS Genetic Test

Frequently Asked Questions

What is RUNX1 Gene Leukemia?
RUNX1 Gene Leukemia is a subtype of acute myeloid leukemia (AML) caused by mutations in the RUNX1 gene, affecting blood and bone marrow.
What are the symptoms of RUNX1 gene leukemia?
Symptoms include fatigue, shortness of breath, pale skin, fever, night sweats, bruising or bleeding easily, enlarged lymph nodes, joint pain, and headaches.
How is RUNX1 gene leukemia diagnosed?
Diagnosis involves blood tests, bone marrow biopsy, and genetic testing such as NGS to identify RUNX1 mutations.
What is the cost of NGS Genetic Test for RUNX1 gene leukemia?
The cost at DNA Labs India is approximately INR 20,000, with free home sample collection available across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test in numerous cities across India.
What does a positive result mean?
A positive result indicates a pathogenic mutation in the RUNX1 gene, which may require consultation with an oncologist for personalized treatment.
Can this test be used for treatment planning?
Yes, identifying specific RUNX1 mutations can help doctors develop targeted treatment plans for AML.
Are there any risks associated with the test?
The test involves a blood draw, which may cause minor bruising or discomfort. Serious risks are minimal.
How accurate is the NGS Genetic Test?
NGS technology is highly accurate for detecting genetic mutations, but results should be interpreted in clinical context.
What should I do before getting tested?
Provide clinical history, consider genetic counseling, and ensure proper sample collection as per instructions.
Is genetic counseling recommended?
Yes, genetic counseling is recommended to understand the implications of test results and family risk.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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