Skip to main content
DNA Labs India

SCN5A Gene Sick sinus syndrome type 1 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

SCN5A Gene Sick sinus syndrome type 1 NGS Genetic Test

Short Name: SCN5A SSS Type 1 NGS Test

Also known as: SCN5A Gene Test for Sick Sinus Syndrome, Sick Sinus Syndrome Type 1 Genetic Test

SCN5A Gene Sick sinus syndrome type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to diagnose SCN5A gene mutations that cause sick sinus syndrome type 1, confirm genetic predisposition, guide treatment decisions, and facilitate family screening for hereditary cardiac conditions.

Test Code
5288
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling to draw a pedigree chart of affected family members.

Method: Venipuncture or finger-prick

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or finger-prick; minimal discomfort expected.

Step 3

Report Delivery

Apply pressure to the collection site to prevent bruising; resume normal activities.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss test implications and family history.
2
During the Test:Blood sample collection; procedure takes about 10-15 minutes.
3
After the Test:Sample sent to lab for NGS analysis; results available in 3-4 weeks.

About This Test

Who Should Get This Test

The purpose of this test is to diagnose SCN5A gene mutations that cause sick sinus syndrome type 1, confirm genetic predisposition, guide treatment decisions, and facilitate family screening for hereditary cardiac conditions.

How to Prepare

  • Fast for 4-6 hours if specified, though not required for this test
  • Bring identification and test requisition form
  • Inform staff of any medications or health conditions

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for SCN5A mutations is crucial for diagnosing hereditary sick sinus syndrome and guiding personalized treatment plans to manage cardiac rhythm disorders."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 ml blood
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger-prick

Sample Stability

Blood samples stable for 24 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Incorrect sample type or volume
  • Missing patient information or consent

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the SCN5A gene, which are associated with sick sinus syndrome type 1.
Positive result: Mutation detected, confirming genetic predisposition; consult a cardiologist for management
Negative result: No mutation found; symptoms may be due to other causes; further testing recommended
Variant of uncertain significance: Genetic counseling advised for interpretation and family planning
⚠️ When to Consult a Doctor:

Consult a healthcare provider if you experience symptoms like dizziness, fainting, or irregular heartbeat, or have a family history of cardiac disorders, to discuss the need for genetic testing.

Limitations

  • ⚠May not detect all genetic variants or epigenetic factors
  • ⚠Results require clinical correlation for diagnosis
  • ⚠Limited to SCN5A gene; other genes may be involved in similar conditions

Risks & Considerations

  • ●Minor bruising or discomfort at blood draw site
  • ●Rare risk of infection
  • ●Psychological impact of genetic results; counseling recommended

Interfering Factors

  • ●Poor sample quality or contamination
  • ●Hemolyzed blood samples
  • ●Insufficient DNA quantity

Compare With Similar Tests

TestSCN5A Gene Sick sinus syndrome type 1 NGS Genetic TestCardiac Genetic PanelECG TestHolter Monitor Test
ComparisonSCN5A Gene Sick sinus syndrome type 1 NGS Genetic Test

Frequently Asked Questions

What is the SCN5A Gene Sick Sinus Syndrome Type 1 NGS Genetic Test?
It is a genetic test that uses next-generation sequencing to detect mutations in the SCN5A gene, which can cause sick sinus syndrome type 1, a heart rhythm disorder.
Why is this test important?
This test helps diagnose hereditary sick sinus syndrome, guides treatment, and allows for family screening to prevent complications like fainting or sudden cardiac events.
What are the symptoms of SCN5A gene sick sinus syndrome type 1?
Common symptoms include dizziness, fainting, irregular heartbeat, chest pain, shortness of breath, and fatigue, which can vary in severity.
How is the test performed?
A blood sample is collected via venipuncture or finger-prick, and DNA is analyzed using NGS technology to identify mutations in the SCN5A gene.
What is the cost of the test?
The test costs INR 20,000 at DNA Labs India, which includes home sample collection across India.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks after sample collection.
What do the results mean?
A positive result indicates a mutation in the SCN5A gene, confirming genetic predisposition; a negative result means no mutation was found. Genetic counseling is advised for interpretation.
Are there any risks associated with the test?
The test involves minimal risks, such as minor bruising from blood draw. Psychological impacts may occur, so genetic counseling is recommended.
Can insurance cover this test?
Coverage depends on your insurance policy; it is not typically covered under government schemes like PMJAY or CGHS. Check with your insurer for details.
What should I do if I have a positive result?
Consult a cardiologist or genetic specialist for further evaluation, management options, and family screening.
How accurate is the NGS technology?
NGS technology provides high accuracy in detecting genetic mutations, but results should be correlated with clinical findings for diagnosis.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

APOB Gene Hypercholesterolemia type B autosomanl dominant NGS Genetic Test

₹20,000

MICM (Maternally Inherited Cardiomyopathy) Mutation Detection Test

₹10,500

EPHX2 Gene Hypercholesterolemia, familial, due to LDLR defect, modifier of NGS Genetic Test

₹20,000

DSC2 Gene Arrhythmogenic right ventricular cardiomyopathy type 11 NGS Genetic Test

₹20,000

KCNA5 Gene Atrial fibrillation type 7 NGS Genetic Test

₹20,000

MYH6 Gene Atrial septal defect type 3 NGS Genetic Test

₹20,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.