SDHAF2 Gene Pheochromocytoma type 5 NGS Genetic Test
Short Name: SDHAF2 Gene Test
Also known as: SDHAF2 Mutation Test, Pheochromocytoma Type 5 Genetic Test, SDHAF2 Gene Analysis
SDHAF2 Gene Pheochromocytoma type 5 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the SDHAF2 gene for early detection and management of Pheochromocytoma Type 5, facilitating genetic counseling, family screening, and personalized therapeutic interventions.
- Test Code
- 2924
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Genetic counseling is recommended prior to testing.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in the arm using standard venipuncture techniques.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the SDHAF2 gene for early detection and management of Pheochromocytoma Type 5, facilitating genetic counseling, family screening, and personalized therapeutic interventions.
How to Prepare
- Ensure proper identification of the patient
- Use sterile collection equipment
- Label samples correctly
- Transport samples at ambient temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for SDHAF2 mutations can guide personalized management and family screening for hereditary pheochromocytoma."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed samples
- Insufficient sample volume
- Improper labeling
Understanding Your Results
Positive
Pathogenic mutation detected; increased risk for Pheochromocytoma Type 5. Genetic counseling and further clinical evaluation recommended.
Negative
No pathogenic mutation detected; risk may be lower but not eliminated. Clinical correlation advised.
Variant of Uncertain Significance
Genetic variant found but significance unknown; may require additional testing or family studies.
Consult a doctor if you have a family history of pheochromocytoma, experience symptoms like hypertension or palpitations, or receive a positive test result for further management.
Limitations
- ⚠May not detect all genetic variants
- ⚠Requires genetic counseling for interpretation
- ⚠Not a standalone diagnostic tool; clinical correlation needed
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Rare risk of infection
- ●Psychological impact of genetic results
Interfering Factors
- ●Poor sample quality
- ●Contamination during collection
- ●Recent blood transfusions
Compare With Similar Tests
| Test | SDHAF2 Gene Pheochromocytoma type 5 NGS Genetic Test | SDHB Gene Test | SDHC Gene Test | Pheochromocytoma Panel Test |
|---|---|---|---|---|
| Comparison | SDHAF2 Gene Pheochromocytoma type 5 NGS Genetic Test | Tests for mutations in SDHB gene, associated with similar adrenal tumors. | Focuses on SDHC gene mutations linked to paragangliomas. | Comprehensive panel testing multiple genes related to pheochromocytoma. |
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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