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SDHB Gene Pheochromocytoma type 2 NGS Genetic Test

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SDHB Gene Pheochromocytoma type 2 NGS Genetic Test

Short Name: SDHB Pheochromocytoma NGS Test

Also known as: SDHB Gene Mutation Test, Pheochromocytoma Genetic Screening, Hereditary Pheochromocytoma Test

SDHB Gene Pheochromocytoma type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the SDHB gene that are associated with Pheochromocytoma type 2, enabling early diagnosis, risk assessment, and personalized management for patients and at-risk individuals.

Test Code
2928
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

A genetic counseling session is recommended to discuss the test, implications, and draw a pedigree chart of family members. Provide clinical history and doctor's prescription.

Step 2

Laboratory Analysis

Blood sample is collected via venipuncture. For FTA card, one drop of blood is sufficient. Ensure proper labeling and handling.

Step 3

Report Delivery

The sample is sent to the laboratory for analysis. Results are typically available in 3-4 weeks and delivered via online portal, email, or WhatsApp.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling and informed consent are required. Provide detailed clinical and family history.
2
During the Test:Sample collection and processing in the laboratory using NGS technology for accurate mutation detection.
3
After the Test:Report generation and genetic counseling session to interpret results and discuss next steps.

About This Test

Who Should Get This Test

To identify mutations in the SDHB gene that are associated with Pheochromocytoma type 2, enabling early diagnosis, risk assessment, and personalized management for patients and at-risk individuals.

How to Prepare

  • No fasting is required for this test unless specified by your doctor.
  • Avoid strenuous physical activity before sample collection.
  • Bring identification and a doctor's prescription or referral.
  • For home collection, ensure a clean and comfortable environment.

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This NGS-based test is essential for identifying SDHB gene mutations, which are linked to hereditary pheochromocytoma. Early detection can guide surveillance and treatment strategies."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Sample Stability

Blood samples are stable for up to 48 hours at room temperature.
Extracted DNA can be stored for longer periods under appropriate conditions.
Sample Rejection Criteria:
  • Hemolyzed, lipemic, or contaminated samples
  • Insufficient sample volume
  • Incorrect sample type or improper labeling

Understanding Your Results

Results indicate the presence or absence of mutations in the SDHB gene. A positive result suggests an increased risk for Pheochromocytoma type 2, while a negative result may reduce risk but does not eliminate it entirely.
Positive: Pathogenic variant detected in the SDHB gene. Consult a genetic counselor and oncologist for further management and surveillance.
Negative: No pathogenic variant detected. Risk may still exist based on family history; consider periodic monitoring.
Variant of Uncertain Significance (VUS): Further testing, family studies, and clinical correlation are recommended to clarify significance.
⚠️ When to Consult a Doctor:

If you have a family history of pheochromocytoma, experience symptoms like high blood pressure or palpitations, or receive a positive genetic test result, consult a geneticist or oncologist promptly for evaluation and management.

Limitations

  • ⚠May not detect all types of genetic mutations, such as large deletions or rearrangements
  • ⚠Requires interpretation by a qualified geneticist or healthcare provider
  • ⚠Results may have psychological or social implications for patients and families

Risks & Considerations

  • ●Minimal physical risk from blood draw, such as bruising or discomfort
  • ●Psychological impact of results, including anxiety or stress
  • ●Potential for insurance or employment discrimination based on genetic information

Interfering Factors

  • ●Poor sample quality or degradation
  • ●Contamination during sample collection or processing
  • ●Recent blood transfusion may affect DNA analysis

Compare With Similar Tests

TestSDHB Gene Pheochromocytoma type 2 NGS Genetic TestSDHA Gene Mutation TestComprehensive Pheochromocytoma PanelVHL Gene Test
ComparisonSDHB Gene Pheochromocytoma type 2 NGS Genetic Test

Frequently Asked Questions

What is the SDHB Gene Pheochromocytoma Type 2 NGS Genetic Test?
It is a genetic test that uses next-generation sequencing to detect mutations in the SDHB gene, which is associated with hereditary Pheochromocytoma type 2, a rare adrenal tumor.
Why is this test recommended?
This test is recommended for individuals with a family history of pheochromocytoma, symptoms like high blood pressure or palpitations, or to confirm a clinical diagnosis for early management.
How is the test performed?
The test involves collecting a blood sample or extracted DNA, which is analyzed in the laboratory using NGS technology to identify SDHB gene mutations.
What sample is required for the test?
The test requires a blood sample, extracted DNA, or one drop of blood on an FTA card.
Is fasting required before the test?
No, fasting is not required for this test unless specifically instructed by your doctor.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What does a positive result mean?
A positive result indicates a pathogenic mutation in the SDHB gene, increasing the risk for Pheochromocytoma type 2. Consult a genetic counselor and oncologist for further steps.
What if the result is negative?
A negative result means no pathogenic variant was detected, but risk may still exist based on family history. Periodic monitoring may be advised.
Are there any risks to the test?
Risks are minimal, including slight discomfort from blood draw and potential psychological impact from results. Genetic counseling helps mitigate these risks.
How much does the test cost?
The test costs INR 20,000 at DNA Labs India, with home sample collection available across India.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
Who should consider this test?
Individuals with a family history of pheochromocytoma, symptoms suggestive of the condition, or those undergoing genetic counseling for hereditary cancer syndromes should consider this test.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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