Sickle Cell Disease Mutation Screening Test
Short Name: SCD Mutation Screening
Also known as: Sickle Cell Anemia Mutation Test, Hemoglobin S Mutation Screening, SCD Genetic Test
Sickle Cell Disease Mutation Screening Test test available at DNA Labs India for ₹5,250. Uses End Point PCR on Peripheral blood samples. Results in 3-4 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the HBB gene that cause Sickle Cell Disease, enabling early diagnosis, carrier screening, and informed family planning.
- Test Code
- 3195
- Price
- ₹5,250
- Sample Type
- Peripheral blood
- Result Time
- 3-4 days
- Fasting Required
- No
- Method
- End Point PCR
Sample Collection
No special preparation required. Inform the lab about any medications or recent transfusions.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities.
Timeline: 3-4 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the HBB gene that cause Sickle Cell Disease, enabling early diagnosis, carrier screening, and informed family planning.
How to Prepare
- Stay hydrated
- Wear loose clothing for easy access
- Provide accurate medical history
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early screening for Sickle Cell Disease is vital for family planning and managing symptoms. This test provides accurate genetic information for informed decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient volume
- Incorrect container or labeling
Understanding Your Results
Negative
No mutations detected. Normal hemoglobin production. Low risk for Sickle Cell Disease.
Positive
Mutations detected. Indicates carrier status or affected individual. Consult a genetic counselor for management.
If you have a family history of Sickle Cell Disease, experience symptoms like anemia or pain, or test positive, consult a healthcare provider or genetic counselor immediately.
Limitations
- ⚠May not detect all rare mutations
- ⚠Cannot determine disease severity
- ⚠Requires genetic counseling for interpretation
Risks & Considerations
- ●Minimal risk from blood draw: bruising, slight pain, or infection at puncture site
- ●No significant long-term risks
Interfering Factors
- ●Recent blood transfusion
- ●Bone marrow transplant
- ●Certain medications affecting hemoglobin
Compare With Similar Tests
| Test | Sickle Cell Disease Mutation Screening | Hemoglobin Electrophoresis | Sickle Cell Solubility Test |
|---|---|---|---|
| Comparison | Sickle Cell Disease Mutation Screening |
Frequently Asked Questions
What is Sickle Cell Disease Mutation Screening?
Why is this test important?
How is the test performed?
What are the symptoms of Sickle Cell Disease?
Who should get tested?
What does a positive result mean?
Is the test painful?
How long does it take to get results?
Is home collection available?
What is the cost of the test?
Can this test be used for prenatal diagnosis?
How accurate is the test?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.