SPTA1 Gene Spherocytosis type 3 NGS Genetic Test
Short Name: SPTA1 Spherocytosis Type 3 NGS Test
Also known as: SPTA1 Gene Test for Spherocytosis, Hereditary Spherocytosis Type 3 Genetic Test, Alpha-Spectrin Gene Test
SPTA1 Gene Spherocytosis type 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect mutations in the SPTA1 gene associated with hereditary spherocytosis type 3, confirming diagnosis, guiding treatment decisions, and facilitating genetic counseling for affected individuals and their families.
- Test Code
- 5625
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Ensure genetic counseling session is scheduled to discuss family history and test implications.
Method: Venipuncture or finger prick
Laboratory Analysis
A blood sample will be drawn from a vein in the arm or a finger prick for FTA card collection. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities. Results will be available in 3 to 4 weeks.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect mutations in the SPTA1 gene associated with hereditary spherocytosis type 3, confirming diagnosis, guiding treatment decisions, and facilitating genetic counseling for affected individuals and their families.
How to Prepare
- Fast for 8-12 hours if specified by physician
- Avoid strenuous activity before sample collection
- Bring identification and prescription if available
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This genetic test is crucial for confirming hereditary spherocytosis type 3, aiding in treatment planning and genetic counseling for affected families."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Incorrect sample type or container
- Insufficient sample volume
Understanding Your Results
Positive for pathogenic variants
Confirms diagnosis of hereditary spherocytosis type 3. Genetic counseling and treatment planning recommended.
Negative for pathogenic variants
No mutations detected in SPTA1 gene. Consider other genetic or non-genetic causes of spherocytosis.
Variant of uncertain significance
Further testing or family studies may be needed for clarification.
Consult a doctor if you experience symptoms of anemia, have a family history of spherocytosis, or receive a positive test result for guidance on management and treatment.
Limitations
- ⚠May not detect all possible mutations in SPTA1 gene
- ⚠Results require interpretation by a genetic specialist
- ⚠Does not rule out other causes of spherocytosis
Risks & Considerations
- ●Minor pain or bruising at the blood draw site
- ●Rare risk of infection or fainting
Interfering Factors
- ●Poor sample quality or contamination
- ●Hemolyzed blood sample
- ●Insufficient DNA quantity
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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