Thrombophilia Comprehensive Profile Test
Short Name: Thrombophilia Comprehensive Profile
Also known as: Thrombophilia Comprehensive Profile, Hypercoagulability Profile
Thrombophilia Comprehensive Profile Test test available at DNA Labs India for ₹21,000. Uses Electromechanical Clot Detection, Chromogenic, PCR, Immunoturbidimetry on Whole blood samples. Results in Samples accepted Monday/Thursday by 11 am; reports delivered Wednesday/Saturday.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect genetic and acquired thrombophilic factors that increase the risk of venous thromboembolism. It aids in the evaluation of inherited or acquired hypercoagulable states and guides clinicians in planning anticoagulation duration and preventive therapy.
- Test Code
- 3692
- Price
- ₹21,000
- Sample Type
- Whole blood
- Result Time
- Samples accepted Monday/Thursday by 11 am; reports delivered Wednesday/Saturday.
- Fasting Required
- Yes
- Method
- Electromechanical Clot Detection, Chromogenic, PCR, Immunoturbidimetry
Sample Collection
Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory. It is recommended that the patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating physician.
Method: Venipuncture
Laboratory Analysis
A trained phlebotomist will collect blood from a vein. Samples are collected in two Blue Top (Sodium Citrate) tubes and two Lavender Top (EDTA) tubes. Mix tubes thoroughly by inversion.
Report Delivery
Apply pressure at the venipuncture site for a few minutes. You can resume normal activities immediately, unless otherwise advised by your physician.
Timeline: Samples accepted Monday/Thursday by 11 am; reports delivered Wednesday/Saturday.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect genetic and acquired thrombophilic factors that increase the risk of venous thromboembolism. It aids in the evaluation of inherited or acquired hypercoagulable states and guides clinicians in planning anticoagulation duration and preventive therapy.
How to Prepare
- 6 mL whole blood in 2 Blue Top (Sodium Citrate) tubes. Mix thoroughly by inversion.
- 5 mL (3 mL min.) whole blood in 2 Lavender Top (EDTA) tubes.
- Transport to Lab within 4 hours.
- If transport is delayed, prepare PPP within 1 hour of collection: centrifuge at 3600 rpm for 15 minutes, transfer supernatant to a clean plastic tube, centrifuge again at 3600 rpm for 15 minutes, transfer PPP to a labelled clean plastic screw-capped vial. Freeze immediately. Ship frozen. Do not thaw.
- For EDTA tubes: Ship refrigerated. Do not freeze.
- Overnight fasting is preferred.
- Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Thrombophilia testing should be done in a stable state, remote from the acute event, to avoid false results."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Incorrect tube volume or ratio
- Samples received without Coagulation Requisition Form
- Frozen EDTA samples
- Samples outside 72-hour stability window
Understanding Your Results
Consult your doctor if you have symptoms like unexplained leg pain, swelling, chest pain, shortness of breath, or if you have a family history of clotting disorders. An abnormal result from this test should be reviewed with a hematologist.
Limitations
- ⚠Testing should be performed remote from an acute thrombotic episode.
- ⚠A single abnormal value requires careful correlation with clinical history.
- ⚠MTHFR polymorphism testing has limited clinical utility in thrombosis evaluation.
- ⚠Results may be unreliable during pregnancy or while on anticoagulants.
Risks & Considerations
- ●Bruising at the puncture site
- ●Bleeding
- ●Infection
- ●Feeling light-headed
Interfering Factors
- ●Acute thrombosis or acute illness may alter Protein C, Protein S, and Antithrombin levels.
- ●Heparin decreases antithrombin levels.
- ●Warfarin decreases Protein C and Protein S levels.
- ●Pregnancy and inflammatory conditions can affect coagulation test results.
- ●Lupus anticoagulant testing may be affected by anticoagulant therapy.
Frequently Asked Questions
What is the Thrombophilia Comprehensive Profile Test?
Why is this test ordered?
How much does the test cost in India?
Does this test require fasting?
Which sample is used for the test?
Can I take my regular medicines before the test?
What do abnormal results mean?
Are there any risks with this blood test?
How long does the test take?
Is the test covered by insurance?
Does DNA Labs India provide home collection?
Who should get this test?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.