Thyroid Prognostication NGS Panel Test
Short Name: Thyroid NGS Panel
Also known as: Thyroid Cancer NGS Panel, Thyroid Prognostic Panel
Thyroid Prognostication NGS Panel Test test available at DNA Labs India for ₹34,000. Uses Next-Generation Sequencing (NGS) on Blood samples. Results in Results are typically available within 4 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The primary purpose of the Thyroid Prognostication NGS Panel is to provide prognostic information for patients diagnosed with thyroid cancer. It helps in identifying genetic mutations that are associated with aggressive tumor behavior, increased risk of recurrence, and potential resistance to conventional therapies. This information is crucial for risk stratification, guiding the intensity of treatment (e.g., surgery, radioactive iodine, targeted therapy), and establishing a surveillance plan. Additionally, the panel can uncover actionable mutations that may be targeted by FDA-approved drugs, offering personalized therapeutic options. Overall, the test aims to improve clinical outcomes by enabling precision medicine approaches in thyroid cancer management.
- Test Code
- 6304
- CPT Code
- 81479
- ICD Code
- E07.9
- Price
- ₹34,000
- Sample Type
- Blood
- Result Time
- Results are typically available within 4 weeks after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation is required. However, inform your healthcare provider about any medications you are taking, as some drugs may affect test results.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. The procedure is quick and causes minimal discomfort.
Report Delivery
You may resume normal activities immediately. There are no restrictions after the test.
Timeline: Results are typically available within 4 weeks after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Thyroid Prognostication NGS Panel is to provide prognostic information for patients diagnosed with thyroid cancer. It helps in identifying genetic mutations that are associated with aggressive tumor behavior, increased risk of recurrence, and potential resistance to conventional therapies. This information is crucial for risk stratification, guiding the intensity of treatment (e.g., surgery, radioactive iodine, targeted therapy), and establishing a surveillance plan. Additionally, the panel can uncover actionable mutations that may be targeted by FDA-approved drugs, offering personalized therapeutic options. Overall, the test aims to improve clinical outcomes by enabling precision medicine approaches in thyroid cancer management.
How to Prepare
- No fasting required
- Avoid alcohol for 24 hours prior to sample collection
- Inform the lab if you have had a blood transfusion in the last 3 months
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This panel provides critical prognostic information for thyroid cancer management, guiding treatment decisions and surveillance strategies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Incorrect sample volume
- Sample received after 7 days of collection
- Label mismatch or missing patient information
Understanding Your Results
BRAF V600E mutation detected
Associated with papillary thyroid cancer, higher risk of recurrence, and potential benefit from targeted therapy (e.g., BRAF inhibitors).
RAS mutation detected
Common in follicular thyroid cancer; may indicate intermediate risk; targeted therapies may be considered.
RET fusion or mutation detected
Seen in medullary thyroid cancer; may be hereditary; targeted therapy with RET inhibitors may be effective.
TERT promoter mutation detected
Associated with aggressive tumor behavior and poorer prognosis; may influence treatment intensity.
TP53 mutation detected
Indicates high-risk, poorly differentiated or anaplastic thyroid cancer; may be resistant to conventional therapy.
No pathogenic mutations detected
Lower risk of aggressive disease; however, clinical correlation is essential.
Consult your oncologist or endocrinologist if you have been diagnosed with thyroid cancer and are considering this test, or if you have a family history of thyroid cancer. Also, consult if you experience new symptoms such as a lump in the neck, hoarseness, or difficulty swallowing.
Limitations
- ⚠This test detects somatic mutations in blood; it does not detect germline mutations unless specifically requested
- ⚠Not all genes associated with thyroid cancer are included; a negative result does not rule out genetic alterations
- ⚠Results should be interpreted in conjunction with clinical and histopathological findings
- ⚠The test is not intended for screening or diagnosis of thyroid cancer in asymptomatic individuals
- ⚠Turnaround time may be extended if repeat testing is required
Risks & Considerations
- ●Minimal risk of bruising or bleeding at the puncture site
- ●Rare risk of infection
- ●Psychological distress from unexpected genetic findings
Interfering Factors
- ●Presence of hematologic malignancies may cause clonal hematopoiesis interference
- ●Low tumor fraction in blood sample may lead to false negatives
- ●Prior chemotherapy or radiation may affect mutation detection
- ●Sample degradation due to improper handling or storage
Compare With Similar Tests
| Test | Thyroid Prognostication NGS Panel | Thyroid Function Test (TFT) | Thyroid Ultrasound | Fine Needle Aspiration (FNA) Biopsy | Thyroid Cancer Gene Expression Classifier |
|---|---|---|---|---|---|
| Comparison | Thyroid Prognostication NGS Panel |
Frequently Asked Questions
What is the Thyroid Prognostication NGS Panel?
Who should get this test?
What is the cost of the test?
Is fasting required?
How is the sample collected?
How long does it take to get results?
Does the test detect hereditary mutations?
Can this test be done at home?
What genes are included in the panel?
Are there any risks?
Will insurance cover this test?
How should I interpret the results?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.