Skip to main content
DNA Labs India

VNTR Chimerism Study [PRE BMT] Test

DNA Labs India | ISO 9001:2015 Certified

VNTR Chimerism Study [PRE BMT] Test

Short Name: VNTR Chimerism Pre-BMT

Also known as: VNTR Analysis, Chimerism Study, Pre-Bone Marrow Transplant Chimerism Test

VNTR Chimerism Study [PRE BMT] Test test available at DNA Labs India for ₹7,500. Uses End Point PCR on Peripheral Blood samples. Results in 3-4 days. Free home collection in 300+ cities across India.

Genetic TestAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the VNTR Chimerism Study [PRE BMT] is to evaluate the baseline chimerism status before bone marrow transplant, monitor donor cell engraftment post-transplant, detect early signs of graft failure or rejection, and assist in managing transplant-related complications such as graft-versus-host disease.

Test Code
3233
Price
₹7,500
Sample Type
Peripheral Blood
Result Time
3-4 days
Fasting Required
No
Method
End Point PCR
Step 1

Sample Collection

Ensure a doctor's prescription is available. No specific fasting required, but follow any instructions from the healthcare provider.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in the arm using standard venipuncture technique.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Keep the sample cool during transport.

Timeline: 3-4 days

Patient Instructions

1
Before the Test:Obtain a doctor's prescription. No fasting required, but ensure proper identification for recipient and donor samples.
2
During the Test:Blood samples are collected from recipient and donor, processed in the lab using VNTR analysis.
3
After the Test:Results are available in 3-4 days. Follow up with your healthcare provider for interpretation.

About This Test

Who Should Get This Test

The purpose of the VNTR Chimerism Study [PRE BMT] is to evaluate the baseline chimerism status before bone marrow transplant, monitor donor cell engraftment post-transplant, detect early signs of graft failure or rejection, and assist in managing transplant-related complications such as graft-versus-host disease.

How to Prepare

  • Collect 2 ml peripheral blood in EDTA tube
  • Label samples correctly for recipient and donor
  • Transport with cool pack to maintain stability

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is essential for evaluating donor-recipient compatibility before bone marrow transplant to ensure successful engraftment."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypePeripheral Blood
Sample Volume2 ml
ContainerEDTA Vacutainer
Collection MethodVenipuncture

Sample Stability

Stable for 24 hours at 2-8°C
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Incorrect tube type
  • Insufficient volume

Understanding Your Results

Results are expressed as a percentage of donor cells in the recipient's blood. Higher percentages indicate better engraftment, while lower levels may suggest graft failure or rejection.
A donor cell percentage close to 100% indicates full engraftment.
Mixed chimerism (partial donor cells) may require monitoring or intervention.
Consult with a transplant specialist for personalized interpretation based on clinical context.
⚠️ When to Consult a Doctor:

Consult a doctor if chimerism levels are low or declining, if there are signs of graft failure such as infection or cytopenias, or if unexplained symptoms occur post-transplant.

Limitations

  • Detection limit may vary based on assay sensitivity
  • Requires prior DNA profiles of donor and recipient
  • Not suitable for detecting microchimerism below threshold

Risks & Considerations

  • Minor bruising at puncture site
  • Rare infection risk
  • Fainting or dizziness during blood draw

Interfering Factors

  • Recent blood transfusion
  • Sample contamination
  • Improper storage or handling

Frequently Asked Questions

What is VNTR Chimerism Study?
VNTR Chimerism Study is a DNA test that uses Variable Number Tandem Repeats analysis to detect the presence of donor and recipient cells, often used before and after bone marrow transplant.
Why is this test done before BMT?
It establishes a baseline chimerism status to monitor engraftment and detect graft failure early post-transplant.
How is the test performed?
Blood samples from recipient and donor are analyzed using End Point PCR to quantify donor cell percentage.
What is the cost of the test?
The cost is INR 7500, including free home sample collection across India.
Is home collection available?
Yes, free home sample collection is available for online bookings in numerous cities.
How long does it take to get results?
Results are typically available within 3-4 days.
What do the results mean?
Results show the percentage of donor cells; higher percentages indicate better engraftment, while lower levels may require medical attention.
Are there any risks?
Risks are minimal, including minor bruising or infection at the blood draw site.
Do I need a doctor's prescription?
Yes, a doctor's prescription is required, except for surgery, pregnancy, or travel abroad cases.
Can this test be done for children?
Yes, it is suitable for all ages, but pediatric cases should be discussed with a healthcare provider.
What is the accuracy of the test?
VNTR analysis is highly accurate and sensitive for detecting chimerism, with reliable results when performed correctly.
How should I prepare for the test?
No special preparation is needed, but ensure proper identification and follow any instructions from your doctor.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.