Warfarin Therapeutic Response Predictive Assay (VKORC1 & CYP2C9) Test
Short Name: VKORC1 & CYP2C9 Assay
Also known as: VKORC1 & CYP2C9 Test, Warfarin Genetic Test, Pharmacogenomic Test for Warfarin
Warfarin Therapeutic Response Predictive Assay (VKORC1 & CYP2C9) Test test available at DNA Labs India for ₹6,000. Uses End Point PCR + RFLP on Peripheral blood samples. Results in 3-4 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify genetic variants in VKORC1 and CYP2C9 genes that affect warfarin metabolism, enabling personalized dosing to optimize therapeutic outcomes and minimize risks.
- Test Code
- 3237
- Price
- ₹6,000
- Sample Type
- Peripheral blood
- Result Time
- 3-4 days
- Fasting Required
- No
- Method
- End Point PCR + RFLP
Sample Collection
Ensure a doctor's prescription is available. No fasting required. Inform the technician of any medications or health conditions.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm using a sterile needle.
Report Delivery
Apply pressure to the puncture site to stop bleeding. Resume normal activities.
Timeline: 3-4 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify genetic variants in VKORC1 and CYP2C9 genes that affect warfarin metabolism, enabling personalized dosing to optimize therapeutic outcomes and minimize risks.
How to Prepare
- Doctor's prescription is required
- Not applicable for surgery, pregnancy, or travel abroad cases
- Home collection available for online bookings
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This genetic test is crucial for patients on warfarin to avoid adverse effects like bleeding. It helps in tailoring the dose based on individual genetics, improving safety and efficacy."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient volume
- Incorrect container
- Missing prescription
Understanding Your Results
Normal warfarin sensitivity, standard dose may be appropriate
Intermediate sensitivity, dose adjustment may be needed
High sensitivity, lower dose required to avoid bleeding
Normal metabolism, standard dosing
Reduced metabolism, dose reduction recommended
Poor metabolism, significant dose reduction required
Consult your doctor immediately if you experience symptoms of warfarin overdose such as unusual bleeding, bruising, or if your INR is consistently out of range.
Limitations
- ⚠Test only analyzes specific variants in VKORC1 and CYP2C9 genes
- ⚠Does not account for other factors like diet, drug interactions, or liver function
- ⚠Results should be interpreted in conjunction with clinical assessment
Risks & Considerations
- ●Minimal risk from blood draw: bruising, infection, or dizziness
Interfering Factors
- ●Recent blood transfusions
- ●DNA contamination in sample
- ●Hemolyzed blood sample
Compare With Similar Tests
| Test | Warfarin Therapeutic Response Predictive Assay (VKORC1 & CYP2C9) | INR Test | Prothrombin Time Test | CYP2C9 Genotyping | Pharmacogenomic Panel |
|---|---|---|---|---|---|
| Comparison | Warfarin Therapeutic Response Predictive Assay (VKORC1 & CYP2C9) | Measures blood clotting time, while genetic test predicts response | Assesses clotting function, not genetic factors | Similar but may not include VKORC1 | Broader panel including multiple genes |
Frequently Asked Questions
What is the Warfarin Therapeutic Response Predictive Assay?
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Your Data Privacy
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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