WT1 Gene Wilms tumor type 1, familial NGS Genetic Test
Short Name: WT1 Gene NGS Test
Also known as: WT1 Gene Mutation Test, Wilms Tumor Genetic Test
WT1 Gene Wilms tumor type 1, familial NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next-Generation Sequencing) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect mutations in the WT1 gene for early diagnosis of familial Wilms tumor, assess risk in family members, guide targeted treatment, and support genetic counseling.
- Test Code
- 5516
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- NGS (Next-Generation Sequencing)
Sample Collection
Genetic counseling is recommended to discuss test implications and family history. No specific preparation is required.
Method: Venipuncture or FTA card collection
Laboratory Analysis
A blood sample will be collected by a trained phlebotomist using standard venipuncture or FTA card method.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Avoid heavy lifting with the arm used for collection.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect mutations in the WT1 gene for early diagnosis of familial Wilms tumor, assess risk in family members, guide targeted treatment, and support genetic counseling.
How to Prepare
- Ensure proper patient identification and labeling
- Use sterile equipment and follow aseptic techniques
- Collect sample in appropriate container (EDTA tube or FTA card)
- Transport sample at ambient room temperature as specified
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"As an obstetrician-gynecologist, I recommend genetic testing for families with a history of Wilms tumor to assess risk and plan for early intervention, especially in prenatal or pediatric settings."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Hemolyzed or contaminated sample
- Improper labeling or documentation
- Sample not stored or transported correctly
Understanding Your Results
Positive (Pathogenic variant detected)
Increased risk for Wilms tumor. Genetic counseling and clinical monitoring are advised.
Negative (No pathogenic variant detected)
No mutation identified, but clinical symptoms may require further investigation. Family risk assessment may still be needed.
Variant of uncertain significance
Further testing or family studies recommended to clarify clinical significance.
Consult a geneticist, oncologist, or nephrologist if symptoms persist, family history is positive, or for interpretation of test results and management planning.
Limitations
- ⚠May not detect all types of WT1 gene mutations
- ⚠Results require interpretation by a genetic specialist
- ⚠Not a standalone diagnostic tool; clinical correlation is essential
- ⚠Variant of uncertain significance may require additional testing
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Rare risk of infection or hematoma
- ●Psychological impact of genetic results, mitigated by counseling
Interfering Factors
- ●Sample degradation or contamination
- ●Technical errors during sequencing
- ●Insufficient DNA quantity or quality
Compare With Similar Tests
| Test | WT1 Gene Wilms tumor type 1, familial NGS Genetic Test | Sanger Sequencing | Renal Ultrasound |
|---|---|---|---|
| Comparison | WT1 Gene Wilms tumor type 1, familial NGS Genetic Test |
Frequently Asked Questions
What is the WT1 Gene Wilms Tumor NGS Genetic Test?
Who should consider this test?
How is the test performed?
What is the cost of the test?
How long does it take to get results?
Is the test accurate?
What are the symptoms of Wilms tumor?
Can this test be done at home?
Is genetic counseling required before the test?
What if the test is positive?
Are there any risks to the test?
How do I book the test?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.