ANCA (Anti Neutrophil Cytoplasmic Antibodies) Positive Reflex to ANCA-MPO & ANCA-PR3 Test
Also known as: ANCA-MPO Test, ANCA-PR3 Test, Anti-Neutrophil Cytoplasmic Antibodies Test
ANCA (Anti Neutrophil Cytoplasmic Antibodies) Positive Reflex to ANCA-MPO & ANCA-PR3 Test test available at DNA Labs India for ₹5,000. Uses Immunofluorescence Assay, EIA on Serum samples. Results in Reports are available next day by 6 pm after sample collection on Mon/Wed/Fri by 9 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect the presence of ANCA antibodies, specifically MPO and PR3, to diagnose ANCA-associated vasculitis and guide treatment decisions.
- Test Code
- 115
- Price
- ₹5,000
- Sample Type
- Serum
- Result Time
- Reports are available next day by 6 pm after sample collection on Mon/Wed/Fri by 9 am.
- Fasting Required
- Yes (12 hours)
- Method
- Immunofluorescence Assay, EIA
Sample Collection
Overnight fasting is preferred. Inform your doctor about any medications or supplements you are taking.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities unless advised otherwise.
Timeline: Reports are available next day by 6 pm after sample collection on Mon/Wed/Fri by 9 am.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect the presence of ANCA antibodies, specifically MPO and PR3, to diagnose ANCA-associated vasculitis and guide treatment decisions.
How to Prepare
- Fast for 8-12 hours before the test if preferred
- Wear clothing with loose sleeves for easy access
- Stay hydrated unless otherwise instructed
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for diagnosing ANCA-associated vasculitis, enabling early treatment to prevent organ damage."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic samples
- Insufficient sample volume
- Improper labeling or documentation
Understanding Your Results
Positive ANCA with MPO or PR3
Suggests ANCA-associated vasculitis; further evaluation needed
Negative ANCA
No detectable ANCA antibodies; vasculitis less likely but not ruled out
Weak positive
May require repeat testing or correlation with symptoms
Consult a rheumatologist or immunologist if you have symptoms like persistent joint pain, unexplained fatigue, or blood in urine, and if your test results are positive or inconclusive.
Limitations
- ⚠May not detect all cases of ANCA-associated vasculitis
- ⚠Possible cross-reactivity with other antibodies
- ⚠Results should be interpreted in conjunction with clinical symptoms and other tests
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rarely, infection or dizziness
Interfering Factors
- ●Recent infections or vaccinations
- ●Certain medications like antibiotics or anti-inflammatory drugs
- ●Improper sample handling or storage
- ●Other autoimmune conditions
Frequently Asked Questions
What is the ANCA Positive Reflex Test?
Why is this test done?
What are the symptoms of ANCA-associated vasculitis?
How is the sample collected?
Is fasting required for this test?
How long does it take to get results?
What does a positive result mean?
What is the cost of the test?
Is home collection available?
How accurate is the test?
Can this test diagnose other conditions?
What should I do if my test is positive?
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₹1,404Reference Laboratory Services
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