Anti ds DNA Antibody Crithidia IFA Test
Short Name: Anti-dsDNA IFA Test
Also known as: Anti-dsDNA Antibody Test, Crithidia IFA Test, Double-Stranded DNA Antibody Test
Anti ds DNA Antibody Crithidia IFA Test test available at DNA Labs India for ₹1,989. Uses Immunofluorescence Assay on Serum samples. Results in Same day report, with sample collection daily by 11 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the Anti ds DNA Antibody Crithidia IFA Test is to identify the presence of anti-dsDNA antibodies in the blood, which are highly specific markers for systemic lupus erythematosus. This aids in confirming a lupus diagnosis, differentiating it from other autoimmune conditions, and monitoring disease progression or flares. It is particularly useful in patients with clinical symptoms suggestive of lupus or those with positive antinuclear antibody (ANA) tests requiring further evaluation.
- Test Code
- 139
- Price
- ₹1,989
- Sample Type
- Serum
- Result Time
- Same day report, with sample collection daily by 11 am.
- Fasting Required
- Yes (8 hours)
- Method
- Immunofluorescence Assay
Sample Collection
Overnight fasting for 8-12 hours is preferred to ensure sample quality. Avoid strenuous activity before the test.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm using a sterile needle. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities unless advised otherwise.
Timeline: Same day report, with sample collection daily by 11 am.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Anti ds DNA Antibody Crithidia IFA Test is to identify the presence of anti-dsDNA antibodies in the blood, which are highly specific markers for systemic lupus erythematosus. This aids in confirming a lupus diagnosis, differentiating it from other autoimmune conditions, and monitoring disease progression or flares. It is particularly useful in patients with clinical symptoms suggestive of lupus or those with positive antinuclear antibody (ANA) tests requiring further evaluation.
How to Prepare
- Collect 2 mL (minimum 1 mL) of blood in a Serum Separator Tube (SST)
- Ship the sample refrigerated or frozen to maintain stability
- Ensure proper labeling and documentation of the sample
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This test is essential for diagnosing systemic lupus erythematosus and monitoring disease activity, helping to guide treatment decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed, lipemic, or improperly stored samples
- Insufficient sample volume or unlabeled specimens
- Samples older than stability guidelines
Understanding Your Results
Positive
Presence of anti-dsDNA antibodies, highly suggestive of systemic lupus erythematosus. Correlates with disease activity and may indicate renal involvement. Further clinical evaluation is recommended.
Negative
No detectable anti-dsDNA antibodies. Does not rule out lupus entirely, as some patients may have negative results. Clinical correlation and repeat testing may be needed.
Consult a doctor if you experience symptoms such as persistent fatigue, joint pain, skin rashes, or if your test results are positive. Regular follow-up is advised for monitoring in autoimmune conditions.
Limitations
- ⚠False positives can occur in other autoimmune conditions like mixed connective tissue disease
- ⚠The test may not detect all anti-dsDNA antibody subtypes
- ⚠Results should be interpreted in conjunction with clinical findings and other laboratory tests
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Rare risk of infection or dizziness
- ●Very low risk of excessive bleeding
Interfering Factors
- ●Hemolyzed or lipemic samples may affect test accuracy
- ●Recent blood transfusions or immunosuppressive therapy could influence results
- ●Storage and handling conditions of the sample prior to testing
Compare With Similar Tests
| Test | Anti ds DNA Antibody Crithidia IFA Test | ANA (Antinuclear Antibody) Test | Complement C3 and C4 Tests |
|---|---|---|---|
| Comparison | Anti ds DNA Antibody Crithidia IFA Test | ANA is a broader screening test for autoimmune diseases, while anti-dsDNA IFA is specific for lupus. A positive ANA may lead to anti-dsDNA testing for confirmation. | These tests measure complement proteins, which may be low in active lupus. They are often used alongside anti-dsDNA to assess disease activity. |
Frequently Asked Questions
What is the Anti ds DNA Antibody Crithidia IFA Test?
Why is this test recommended?
How is the test performed?
What does a positive result mean?
Is fasting required for this test?
What is the cost of the test at DNA Labs India?
How soon will I get my results?
Are there any risks associated with the test?
Can this test diagnose other autoimmune diseases?
How should I prepare for the test?
Is home sample collection available?
What if my test is negative but I still have symptoms?
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₹4,500Reference Laboratory Services
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