BCL2 Test
Also known as: BCL2 gene mutation test, BCL2 FISH test, BCL2 gene rearrangement
BCL2 Test test available at DNA Labs India for ₹5,250. Uses FISH on Bone Marrow / Peripheral Blood samples. Results in Results are typically available within 3-4 days after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of the BCL2 gene mutation test is to detect chromosomal abnormalities involving the BCL2 gene, particularly the t(14;18) translocation, which is characteristic of follicular lymphoma. This test aids in diagnosing B-cell lymphomas, assessing prognosis, and guiding treatment decisions. It is also used for monitoring minimal residual disease and detecting relapse. By identifying BCL2 rearrangements, clinicians can choose targeted therapies, such as BCL2 inhibitors, and tailor treatment plans to individual patients. The test is non-invasive, simple, and provides critical information for managing cancer effectively.
- Test Code
- 6038
- CPT Code
- 88271
- ICD Code
- C91.1
- Price
- ₹5,250
- Sample Type
- Bone Marrow / Peripheral Blood
- Result Time
- Results are typically available within 3-4 days after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- FISH
Sample Collection
No special preparation is required. Inform your doctor about any medications you are taking. A doctor's prescription is mandatory for this test.
Method: Cheek swab or blood draw
Laboratory Analysis
A blood sample will be drawn from a vein in your arm, or a bone marrow aspiration may be performed if indicated. The procedure is quick and minimally invasive.
Report Delivery
You can resume normal activities immediately. There may be slight bruising at the puncture site, which is normal and resolves on its own.
Timeline: Results are typically available within 3-4 days after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the BCL2 gene mutation test is to detect chromosomal abnormalities involving the BCL2 gene, particularly the t(14;18) translocation, which is characteristic of follicular lymphoma. This test aids in diagnosing B-cell lymphomas, assessing prognosis, and guiding treatment decisions. It is also used for monitoring minimal residual disease and detecting relapse. By identifying BCL2 rearrangements, clinicians can choose targeted therapies, such as BCL2 inhibitors, and tailor treatment plans to individual patients. The test is non-invasive, simple, and provides critical information for managing cancer effectively.
How to Prepare
- Sample type: Bone Marrow / Peripheral Blood
- Container: Sodium Heparin Vacutainer (2ml)
- Preparation: Ambient temperature
- Fasting: Not required
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"BCL2 gene rearrangement is a key marker in hematological malignancies. Early detection through FISH testing can guide targeted therapy and improve patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Clotted sample
- Hemolyzed sample
- Incorrect container
- Insufficient volume
Understanding Your Results
Negative
No BCL2 gene rearrangement detected. This suggests a lower likelihood of BCL2-associated lymphoma, but clinical correlation is necessary.
Positive
BCL2 gene rearrangement detected. This is supportive of a diagnosis of follicular lymphoma or other B-cell malignancies. Further evaluation and staging are recommended.
If you experience persistent symptoms such as unexplained weight loss, fever, night sweats, or enlarged lymph nodes, consult an oncologist. A positive BCL2 test result should be discussed with your doctor to plan appropriate treatment.
Limitations
- ⚠FISH only detects specific known rearrangements; other mutations may not be identified
- ⚠Test is not diagnostic for all cancer types
- ⚠Results should be interpreted in conjunction with clinical findings and other diagnostic tests
Risks & Considerations
- ●Minimal risk of bleeding or bruising at the puncture site
- ●Rare risk of infection
- ●No significant radiation exposure from FISH testing
Interfering Factors
- ●Recent chemotherapy or radiation therapy may affect test results
- ●Inadequate sample volume or improper handling
- ●Clotted blood sample
- ●Concurrent infections may cause false positives
Compare With Similar Tests
| Test | BCL2 | BCL2 FISH | BCL6 FISH | MYC FISH |
|---|---|---|---|---|
| Comparison | BCL2 |
Frequently Asked Questions
What is the BCL2 gene?
What is the cost of BCL2 testing at DNA Labs India?
What sample is required for the BCL2 test?
Do I need to fast before the BCL2 test?
How long does it take to get BCL2 test results?
Is home sample collection available for BCL2 test?
What is the method used for BCL2 testing?
What does a positive BCL2 test result mean?
Can BCL2 test be done without a doctor's prescription?
Is the BCL2 test covered by insurance?
What are the symptoms of BCL2 gene mutation?
How accurate is the BCL2 FISH test?
Related Tests
B-Cell Rearrangement Detection Test
₹22,000Acute Lymphoblastic Leukemia (ALL) Cytogenetics Panel Test
₹20,000Epstein-Barr Virus Early RNA (EBER-ISH) In-Situ-Hybridization Test
₹6,000OncoPro NCCN Lung Cancer Panel with PD-L1 Test
₹140,400Acute Myeloid Leukemia (AML) Cytogenetics Panel Test
₹23,000AML ETO t(8;21) Gene Rearrangement PCR Qualitative Test
₹6,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.