BCR/ABL Major Quantitative Test
Short Name: BCR/ABL Major Quantitative
Also known as: BCR-ABL Quantitative Test, Philadelphia Chromosome Test
BCR/ABL Major Quantitative Test test available at DNA Labs India for ₹10,200. Uses Real-Time PCR on Whole Blood, Bone Marrow Aspirate samples. Results in Results available in 3 working days; reports delivered via email, online portal, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The primary purpose of the BCR/ABL Major Quantitative Test is to detect the presence and measure the amount of the BCR-ABL1 fusion gene in patients suspected of or diagnosed with chronic myeloid leukemia (CML). This test aids in initial diagnosis, monitoring the effectiveness of treatment such as tyrosine kinase inhibitors, and detecting relapse or minimal residual disease.
- Test Code
- 3259
- Price
- ₹10,200
- Sample Type
- Whole Blood, Bone Marrow Aspirate
- Result Time
- Results available in 3 working days; reports delivered via email, online portal, or WhatsApp.
- Fasting Required
- No
- Method
- Real-Time PCR
Sample Collection
Patient must sign a consent document and provide any relevant clinical history. No fasting is required.
Method: Venipuncture
Laboratory Analysis
A blood sample is drawn from a vein in the arm using a needle. For bone marrow aspirate, a procedure is performed by a healthcare professional.
Report Delivery
Apply pressure to the puncture site to stop bleeding. Keep the area clean and dry.
Timeline: Results available in 3 working days; reports delivered via email, online portal, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the BCR/ABL Major Quantitative Test is to detect the presence and measure the amount of the BCR-ABL1 fusion gene in patients suspected of or diagnosed with chronic myeloid leukemia (CML). This test aids in initial diagnosis, monitoring the effectiveness of treatment such as tyrosine kinase inhibitors, and detecting relapse or minimal residual disease.
How to Prepare
- Sign the consent form
- Bring clinical history and previous test reports
- No special preparation needed
- Wear loose clothing for easy access
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This quantitative test is vital for monitoring BCR-ABL levels in CML patients, helping to assess treatment efficacy and detect minimal residual disease."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Incorrect sample type or container
- Insufficient sample volume
- Unlabeled or mislabeled samples
Understanding Your Results
Negative or Not Detected
No BCR-ABL1 fusion gene found; suggests absence of CML or successful treatment
Positive with Low Levels
Presence of BCR-ABL1; may indicate early disease or good treatment response
Positive with High Levels
High BCR-ABL1 levels; suggests active disease or treatment failure
If the test results are positive or show increasing levels, consult an oncologist for further evaluation and management.
Limitations
- ⚠Cannot detect all BCR-ABL variants
- ⚠Requires specialized laboratory equipment
- ⚠Results may vary based on sample quality
- ⚠Not a standalone diagnostic; clinical correlation needed
Risks & Considerations
- ●Minor bruising or pain at blood draw site
- ●Rare risk of infection
- ●For bone marrow biopsy, slight risk of bleeding or discomfort
Interfering Factors
- ●Sample contamination
- ●Improper sample handling or storage
- ●Presence of inhibitors in the sample
- ●Technical errors in PCR amplification
Compare With Similar Tests
| Test | BCR/ABL Major Quantitative Test | BCR/ABL Minor Quantitative Test | FISH for BCR-ABL | Conventional Cytogenetics | Complete Blood Count (CBC) |
|---|---|---|---|---|---|
| Comparison | BCR/ABL Major Quantitative Test |
Frequently Asked Questions
What is the BCR/ABL Major Quantitative Test?
Why is this test done?
How is the test performed?
What is the cost of the test?
Is home collection available?
How long does it take to get results?
What do the results mean?
Is fasting required for the test?
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How accurate is the test?
Can this test diagnose leukemia?
What should I do if my results are abnormal?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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