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DNA Labs India

BRAF Mutation Analysis Test

DNA Labs India | ISO 9001:2015 Certified

BRAF Mutation Analysis Test

Short Name: BRAF Mutation Test

Also known as: BRAF Gene Test, BRAF V600E Mutation Analysis, BRAF Mutation Detection

BRAF Mutation Analysis Test test available at DNA Labs India for ₹8,000. Uses PCR, Sequencing on Formalin fixed paraffin embedded tissue block or whole blood samples. Results in Report available within 5-7 business days after sample receipt at the laboratory.. Free home collection in 300+ cities across India.

DiagnosticAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To detect mutations in the BRAF gene for cancer diagnosis, prognosis, and treatment planning, aiding in the selection of targeted therapies.

Test Code
224
Price
₹8,000
Sample Type
Formalin fixed paraffin embedded tissue block or whole blood
Result Time
Report available within 5-7 business days after sample receipt at the laboratory.
Fasting Required
No
Method
PCR, Sequencing
Step 1

Sample Collection

Ensure sample is collected as per instructions. For tissue samples, confirm sufficient tumor content with the pathologist.

Method: Venipuncture for blood, Biopsy for tissue

Step 2

Laboratory Analysis

Blood draw or tissue biopsy performed by a trained healthcare professional. Minor discomfort may be experienced.

Step 3

Report Delivery

Sample is labeled and sent to the laboratory for analysis. Resume normal activities unless otherwise directed.

Timeline: Report available within 5-7 business days after sample receipt at the laboratory.

Patient Instructions

1
Before the Test:No specific preparation required. Ensure sample is collected correctly.
2
During the Test:Sample collection involves a blood draw or biopsy, with minimal risks.
3
After the Test:Report delivery within 5-7 business days. Follow up with your doctor for interpretation.

About This Test

Who Should Get This Test

To detect mutations in the BRAF gene for cancer diagnosis, prognosis, and treatment planning, aiding in the selection of targeted therapies.

How to Prepare

  • For tissue: Submit formalin fixed paraffin embedded tissue block with at least 10% tumor tissue. Ship at room temperature.
  • For blood: Collect 3 mL (min. 2 mL) whole blood in a Lavender top (EDTA) tube. Ship refrigerated. Do not freeze.
  • Duly filled NGS Test Requisition Form (Form 40) is mandatory for all samples.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"BRAF mutation analysis is crucial for identifying patients who may benefit from targeted therapies in cancers such as melanoma and colorectal cancer, improving treatment outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeFormalin fixed paraffin embedded tissue block or whole blood
Sample VolumeFor blood: 3 mL (min. 2 mL); For tissue: Block with ≥10% tumor tissue
ContainerLavender top (EDTA) tube for blood
Collection MethodVenipuncture for blood, Biopsy for tissue

Sample Stability

Room Temperature: Not applicable for tissue blocks
Refrigerator: 72 hours for blood samples
Frozen: Not applicable
Sample Rejection Criteria:
  • Insufficient tumor tissue (<10%) in the paraffin block
  • Incorrect sample type or container
  • Missing or incomplete NGS Test Requisition Form (Form 40)

Understanding Your Results

Results indicate the presence or absence of BRAF mutations, which guide treatment decisions and prognosis for cancer patients.
Positive result: BRAF mutation detected, indicating potential eligibility for targeted therapies such as BRAF inhibitors.
Negative result: No BRAF mutation detected, suggesting standard treatment approaches may be more appropriate.
⚠️ When to Consult a Doctor:

Consult your oncologist immediately upon receiving a positive result or if symptoms persist or worsen despite negative results.

Limitations

  • ⚠Detects only specific BRAF mutations (e.g., V600E), not all variants
  • ⚠False negatives possible with low tumor burden in samples
  • ⚠Does not assess other genetic markers or cancer types beyond BRAF

Risks & Considerations

  • ●Minor bruising or discomfort from blood draw
  • ●Risk of infection or bleeding from biopsy procedure

Interfering Factors

  • ●Inadequate tumor tissue in the sample (<10%)
  • ●Sample contamination during collection or transport
  • ●Degraded DNA from improper storage or handling

Compare With Similar Tests

TestBRAF Mutation Analysis TestKRAS Mutation TestEGFR Mutation Test
ComparisonBRAF Mutation Analysis Test

Frequently Asked Questions

What is a BRAF mutation?
A BRAF mutation is a change in the BRAF gene that can lead to uncontrolled cell growth and is often associated with cancers like melanoma and colorectal cancer.
Why is the BRAF Mutation Analysis Test important?
This test helps in diagnosing cancer, predicting prognosis, and determining if a patient is eligible for targeted therapies that specifically treat BRAF-mutated cancers.
Who should consider getting this test?
Individuals with symptoms of cancer, a family history of BRAF-related cancers, or those undergoing evaluation for targeted therapy eligibility.
How is the test performed?
The test analyzes a tissue or blood sample using PCR and sequencing methods to detect BRAF gene mutations.
What samples are required for the test?
Either a formalin-fixed paraffin-embedded tissue block with at least 10% tumor tissue or 3 mL of whole blood in an EDTA tube.
What is the cost of the BRAF Mutation Analysis Test?
The test costs INR 8000 at DNA Labs India, with a discounted price including home collection across India.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
How long does it take to get results?
Results are typically available within 5-7 business days after the sample is received by the laboratory.
What does a positive test result mean?
A positive result indicates the presence of a BRAF mutation, which may guide the use of targeted therapies for cancer treatment.
What does a negative test result mean?
A negative result means no BRAF mutation was detected, and standard treatment options may be considered.
Are there any risks associated with the test?
Risks are minimal and may include minor bruising from blood draw or infection risk from biopsy, but these are generally low.
How should I prepare for the test?
No special preparation is needed. Ensure the sample is collected as per instructions and the requisition form is filled correctly.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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