Chimerism Split Cell Analysis - Myeloid Cell (CD15) Test
Short Name: CD15 Chimerism Analysis
Also known as: Myeloid Cell Chimerism Test, Post-Transplant CD15 Chimerism Analysis
Chimerism Split Cell Analysis - Myeloid Cell (CD15) Test test available at DNA Labs India for ₹10,500. Uses PCR, STR Analysis, Fragment Analysis on Whole blood or Bone marrow samples. Results in Reports are available within 7 working days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of the Chimerism Split Cell Analysis - Myeloid Cell (CD15) Test is to evaluate the level of donor chimerism in myeloid cells after a bone marrow transplant. This helps in assessing transplant engraftment, monitoring treatment efficacy, diagnosing complications like graft failure or GvHD, and guiding clinical interventions to optimize patient outcomes.
- Test Code
- 293
- Price
- ₹10,500
- Sample Type
- Whole blood or Bone marrow
- Result Time
- Reports are available within 7 working days after sample receipt.
- Fasting Required
- No
- Method
- PCR, STR Analysis, Fragment Analysis
Sample Collection
Indicate the date of bone marrow transplant on the requisition form. No fasting is required, but follow any specific instructions from your healthcare provider.
Method: Venipuncture or Bone Marrow Aspiration
Laboratory Analysis
A healthcare professional will collect a blood sample via venipuncture or bone marrow aspirate using sterile techniques. The sample is placed in an EDTA tube.
Report Delivery
Label the tube correctly and ship it refrigerated to the laboratory. Avoid freezing the sample to maintain integrity.
Timeline: Reports are available within 7 working days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Chimerism Split Cell Analysis - Myeloid Cell (CD15) Test is to evaluate the level of donor chimerism in myeloid cells after a bone marrow transplant. This helps in assessing transplant engraftment, monitoring treatment efficacy, diagnosing complications like graft failure or GvHD, and guiding clinical interventions to optimize patient outcomes.
How to Prepare
- Indicate Date of Bone Marrow Transplant on the form
- Collect 4 ml (2 ml min.) whole blood or bone marrow in a Lavender Top (EDTA) tube
- Ship refrigerated at 2-8°C; do not freeze
- Ensure proper labeling and documentation
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is essential for monitoring graft success and detecting early signs of rejection or relapse after bone marrow transplantation, guiding personalized post-transplant care."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample frozen
- Incorrect tube type
- Insufficient volume
- Missing transplant date information
- Sample hemolyzed or clotted
Understanding Your Results
Likely indicates good engraftment and donor cell dominance; monitor for stability.
Mixed chimerism; may require closer monitoring or therapeutic intervention based on clinical context.
Predominantly host cells; could indicate graft rejection or disease relapse; consult specialist immediately.
If you experience symptoms such as fever, weakness, unexplained bruising, or shortness of breath post-transplant, or if test results show mixed or low chimerism levels, consult your oncologist or hematologist promptly.
Limitations
- ⚠Assesses only myeloid cell lineage, not lymphoid cells
- ⚠May not detect low-level chimerism below detection limits
- ⚠Requires accurate clinical history for interpretation
Risks & Considerations
- ●Minor bruising or pain at the collection site
- ●Rare risk of infection with bone marrow aspiration
- ●Minimal risk from blood draw
Interfering Factors
- ●Improper sample storage (e.g., freezing)
- ●Sample contamination
- ●Incorrect labeling with transplant date
- ●Hemolyzed or clotted samples
Frequently Asked Questions
What is chimerism?
Why is the Myeloid Cell (CD15) test important?
How is the sample collected for this test?
What does a high percentage of donor myeloid cells indicate?
Can this test diagnose graft-versus-host disease (GvHD)?
Is fasting required before the test?
How long does it take to get results?
Is home sample collection available for this test?
What should I do if my test shows mixed chimerism?
Are there any risks associated with the test?
How does this test differ from a full chimerism analysis?
Is the test covered by insurance schemes like PMJAY?
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