Tacrolimus FK506 Test
Also known as: FK506 Level Test, Tacrolimus Concentration Test
Tacrolimus FK506 Test test available at DNA Labs India for ₹5,500. Uses LC-MS/MS on Whole Blood samples. Results in Reports available same day if sample received by 5 pm.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the Tacrolimus FK506 Test is to monitor blood levels of Tacrolimus in transplant patients to assess therapeutic efficacy, prevent toxicity, and adjust doses for optimal immunosuppression. It aids in evaluating patient compliance and is crucial for long-term graft survival.
- Test Code
- 1417
- Price
- ₹5,500
- Sample Type
- Whole Blood
- Result Time
- Reports available same day if sample received by 5 pm.
- Fasting Required
- No
- Method
- LC-MS/MS
Sample Collection
Inform healthcare provider about current medications, especially other immunosuppressants. Ensure sampling is done just before the next dose.
Method: Venipuncture
Laboratory Analysis
Standard venipuncture procedure to collect 3 mL whole blood in an EDTA tube.
Report Delivery
Label the sample with patient details, date, time of sampling, and dose information. Apply pressure to the puncture site.
Timeline: Reports available same day if sample received by 5 pm.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Tacrolimus FK506 Test is to monitor blood levels of Tacrolimus in transplant patients to assess therapeutic efficacy, prevent toxicity, and adjust doses for optimal immunosuppression. It aids in evaluating patient compliance and is crucial for long-term graft survival.
How to Prepare
- Sample should be collected just before the next dose (trough level)
- Provide date and time of sampling, amount and time of last dose
- Ship refrigerated, do not freeze
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Regular monitoring of Tacrolimus trough levels is crucial to balance efficacy and toxicity in transplant patients. Consult your nephrologist for personalized dosing."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Incorrect sample type or volume
- Samples not stored properly or frozen
Understanding Your Results
Subtherapeutic; may increase risk of organ rejection
Range: <5 ng/mL
Generally therapeutic; monitor for clinical response
Range: 5-20 ng/mL
Supratherapeutic; risk of toxicity, consider dose reduction
Range: >20 ng/mL
Consult your doctor if experiencing symptoms like tremors, nausea, kidney dysfunction, or if blood levels are outside the therapeutic range.
Limitations
- ⚠Single trough level may not capture peak levels or overall exposure
- ⚠Variability due to pharmacokinetic differences between patients
Risks & Considerations
- ●Minimal risks from blood draw: bruising, infection, or fainting
Interfering Factors
- ●Other medications affecting CYP3A4 enzymes
- ●Hemolyzed or lipemic samples
- ●Improper sample collection or storage
Compare With Similar Tests
| Test | Tacrolimus FK506 Test | Cyclosporine Test | Sirolimus Test |
|---|---|---|---|
| Comparison | Tacrolimus FK506 Test | Another immunosuppressant drug monitoring test for transplant patients | Monitors levels of sirolimus, another mTOR inhibitor used in transplantation |
Frequently Asked Questions
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