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DNA Labs India

Immunosuppressant Drug Profile 4 Test

DNA Labs India | ISO 9001:2015 Certified

Immunosuppressant Drug Profile 4 Test

Short Name: Immunosuppressant Profile 4

Also known as: TDM for Immunosuppressants, Immunosuppressant Drug Level Test

Immunosuppressant Drug Profile 4 Test test available at DNA Labs India for ₹11,000. Uses LC-MS/MS on Whole Blood samples. Results in Report available same day if sample is received by 5 PM; otherwise, next business day.. Free home collection in 300+ cities across India.

Blood TestAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

To monitor levels of immunosuppressant drugs in patients undergoing treatment for organ transplantation, autoimmune disorders, or cancer, ensuring therapeutic effectiveness and minimizing toxicity.

Test Code
1097
Price
₹11,000
Sample Type
Whole Blood
Result Time
Report available same day if sample is received by 5 PM; otherwise, next business day.
Fasting Required
No
Method
LC-MS/MS
Step 1

Sample Collection

Provide date and time of sampling, dose taken, and time of dosing. Inform physician about all medications.

Method: Venipuncture

Step 2

Laboratory Analysis

Standard blood draw procedure; sample collected in EDTA tube.

Step 3

Report Delivery

Apply pressure to puncture site to prevent bruising. Resume normal activities.

Timeline: Report available same day if sample is received by 5 PM; otherwise, next business day.

Patient Instructions

1
Before the Test:Inform your physician about all medications, supplements, and medical history. No fasting required, but timing relative to drug dose is critical.
2
During the Test:A blood sample will be drawn from a vein in your arm by a trained phlebotomist.
3
After the Test:You can resume normal activities immediately. Apply pressure to the puncture site if needed.

About This Test

Who Should Get This Test

To monitor levels of immunosuppressant drugs in patients undergoing treatment for organ transplantation, autoimmune disorders, or cancer, ensuring therapeutic effectiveness and minimizing toxicity.

How to Prepare

  • Ship sample refrigerated
  • Ideal sampling time: Just before the next dose (Trough levels)
  • Provide date and time of sampling, dose taken, and time of dosing

Doctor's Notes

Reviewed by — MBBS, MD (Biochemistry) · Reg. No. 21504

"Regular monitoring of immunosuppressant drug levels is vital for transplant patients to prevent rejection and minimize toxicity, ensuring long-term graft survival."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole Blood
Sample Volume3 mL (2 mL min.)
ContainerLavender Top (EDTA) Tube
Collection MethodVenipuncture

Sample Stability

Room Temperature: 6 hours
Refrigerator: 1 week
Frozen: Not applicable
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Insufficient sample volume
  • Improperly labeled or stored sample

Understanding Your Results

Levels of immunosuppressant drugs are interpreted by the physician based on patient history, transplant type, and clinical condition.
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Higher levels may indicate toxicity risk (e.g., kidney damage), lower levels may increase rejection risk.

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Elevated levels can lead to side effects like mouth ulcers, low levels may reduce efficacy.

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High levels associated with nephrotoxicity, low levels with graft rejection.

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Monitoring helps balance immunosuppression and avoid complications like edema or infections.

⚠️ When to Consult a Doctor:

If experiencing symptoms like fever, tenderness, swelling, decreased organ function, joint pain, fatigue, or skin rashes while on immunosuppressant therapy.

Limitations

  • Does not replace clinical judgment; levels must be interpreted in context of patient history
  • Reference ranges may vary by laboratory and patient population
  • Test measures total drug levels, not free drug fractions

Risks & Considerations

  • Minor bruising or pain at puncture site
  • Rare risk of infection or excessive bleeding

Interfering Factors

  • Other medications that affect drug metabolism
  • Liver or kidney function impairment
  • Dietary factors (e.g., grapefruit juice)
  • Sample handling or timing errors

Compare With Similar Tests

TestImmunosuppressant Drug Profile 4 TestComplete Blood CountLiver Function TestKidney Function Test
ComparisonImmunosuppressant Drug Profile 4 Test

Frequently Asked Questions

What is the Immunosuppressant Drug Profile 4 Test?
It is a blood test that measures levels of four immunosuppressant drugs: Tacrolimus, Sirolimus, Cyclosporine, and Everolimus, used to monitor therapy in transplant or autoimmune patients.
Why is this test important?
It helps ensure drug levels are therapeutic, preventing organ rejection or disease progression while avoiding toxicity.
What drugs are measured in this test?
Tacrolimus, Sirolimus, Cyclosporine, and Everolimus.
How is the test performed?
A blood sample is drawn and analyzed using LC-MS/MS for accurate drug level measurement.
What is the cost of the test?
The test costs INR 11,000 at DNA Labs India, with free home collection available.
Is home sample collection available?
Yes, free home collection is available across many cities in India for online bookings.
How long does it take to get results?
Results are typically available the same day if the sample is received by 5 PM.
What should I do before the test?
Provide your physician with dosing details and timing. No fasting is required, but sample timing relative to drug dose is crucial.
What are the normal ranges for the drugs?
Ranges vary based on clinical context; your physician will interpret results based on your specific condition.
What do high or low levels indicate?
High levels may indicate toxicity, low levels may risk rejection or disease activity. Consult your doctor for interpretation.
Are there any risks associated with the test?
Risks are minimal, such as minor bruising at the puncture site. Serious complications are rare.
How often should this test be done?
Frequency depends on your treatment plan; your physician will advise based on your stability and clinical needs.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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