CLL Panel Deletion/Duplication Detection Test
Also known as: CLL Genetic Panel, CLL Deletion/Duplication Test, Chronic Lymphocytic Leukemia Genetic Test
CLL Panel Deletion/Duplication Detection Test test available at DNA Labs India for ₹10,500. Uses MLPA on Bone marrow / Peripheral blood samples. Results in 7-10 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the CLL Panel Deletion/Duplication Detection test is to identify genetic abnormalities in genes associated with Chronic Lymphocytic Leukemia (CLL), such as TP53, ATM, and BIRC3. This helps in confirming diagnosis, assessing disease risk, monitoring progression, and guiding targeted treatment decisions to improve patient outcomes.
- Test Code
- 2975
- Price
- ₹10,500
- Sample Type
- Bone marrow / Peripheral blood
- Result Time
- 7-10 days
- Fasting Required
- No
- Method
- MLPA
Sample Collection
Ensure a doctor's prescription is available. Avoid eating or drinking if specified, though fasting is not required. Inform the healthcare provider about any medications or conditions.
Method: Venipuncture
Laboratory Analysis
A blood sample or bone marrow aspirate will be collected by a trained phlebotomist using standard venipuncture or aspiration techniques. The sample is placed in an EDTA vacutainer.
Report Delivery
Transport the sample immediately to the laboratory with a cool pack to maintain stability. Avoid delays to ensure accurate results.
Timeline: 7-10 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the CLL Panel Deletion/Duplication Detection test is to identify genetic abnormalities in genes associated with Chronic Lymphocytic Leukemia (CLL), such as TP53, ATM, and BIRC3. This helps in confirming diagnosis, assessing disease risk, monitoring progression, and guiding targeted treatment decisions to improve patient outcomes.
How to Prepare
- Doctor's prescription is required for the test
- Sample must be transported immediately after collection
- Use an EDTA vacutainer (2ml) for blood or bone marrow
- Maintain sample coolness with a cool pack during transport
- Prescription exceptions apply for surgery, pregnancy, or travel abroad cases
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for identifying genetic abnormalities in CLL, aiding in personalized treatment plans and risk assessment for better patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Incorrect sample container or type
- Sample not transported within stability period
Understanding Your Results
No deletion/duplication detected
Normal finding; no genetic abnormalities identified in the tested genes. Does not rule out CLL entirely.
Deletion detected (e.g., TP53, ATM)
Abnormal finding; indicates genetic alteration associated with CLL, which may influence prognosis and treatment options.
Duplication detected (e.g., BIRC3)
Abnormal finding; suggests genetic change linked to CLL progression, requiring further clinical evaluation.
Multiple abnormalities detected
Abnormal finding; indicates complex genetic profile, often associated with aggressive disease and need for targeted therapy.
Consult a doctor if you experience symptoms of CLL such as enlarged lymph nodes, chronic fatigue, or recurrent infections, or if test results indicate abnormalities for personalized management.
Limitations
- ⚠May not detect all genetic variants or mutations in CLL
- ⚠Results should be correlated with clinical findings and other tests
- ⚠Limited to specific genes included in the panel
- ⚠False negatives or positives possible in rare cases
Risks & Considerations
- ●Minor bruising or discomfort at the collection site
- ●Rare risk of infection or bleeding from bone marrow aspiration
- ●No significant risks for blood sample collection
Interfering Factors
- ●Poor sample quality or hemolysis
- ●Contamination during sample collection or transport
- ●Delayed sample processing beyond stability period
- ●Incorrect sample type or volume
Compare With Similar Tests
| Test | CLL Panel Deletion/Duplication Detection | CLL FISH Panel | BCR-ABL Gene Test | Complete Blood Count (CBC) | Bone Marrow Biopsy |
|---|---|---|---|---|---|
| Comparison | CLL Panel Deletion/Duplication Detection | FISH detects specific chromosomal abnormalities but may have lower resolution for gene-level deletions/duplications compared to MLPA. | Focuses on BCR-ABL fusion, not directly related to CLL genetic panel; used more for other leukemias. | CBC measures blood cell counts but does not provide genetic information; used for initial screening. | Invasive procedure for cellular analysis; genetic tests like this panel offer specific molecular insights. |
Frequently Asked Questions
What is CLL Panel Deletion/Duplication Detection?
Why is this test recommended?
What sample is required for the test?
Is fasting required before the test?
How much does the CLL Panel Deletion/Duplication Detection test cost?
How long does it take to get results?
Is home sample collection available?
What do abnormal results indicate?
Are there any risks associated with the test?
Do I need a doctor's prescription for this test?
How is the test performed?
What should I do if I have symptoms of CLL?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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