CML MRD1 Viral Load Quantitative Test
Short Name: CML MRD1 Viral Load Test
Also known as: BCR-ABL1 Quantitative PCR Test, CML Minimal Residual Disease Test
CML MRD1 Viral Load Quantitative Test test available at DNA Labs India for ₹10,200. Uses Real Time PCR on Whole Blood samples. Results in 3 Working Days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the CML MRD1 Viral Load Quantitative Test is to quantify the BCR-ABL1 gene levels in the blood of CML patients. This helps in assessing the effectiveness of treatment, determining if a patient has achieved a major molecular response, and monitoring for any signs of disease recurrence. It is a key tool in personalized medicine for CML management.
- Test Code
- 3288
- Price
- ₹10,200
- Sample Type
- Whole Blood
- Result Time
- 3 Working Days
- Fasting Required
- No
- Method
- Real Time PCR
Sample Collection
Sign a consent document and bring any clinical history of the patient for the CML MRD1 Viral Load Quantitative Test.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in the arm using standard venipuncture procedure.
Report Delivery
Apply pressure to the puncture site with a bandage to prevent bleeding. Resume normal activities unless advised otherwise.
Timeline: 3 Working Days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the CML MRD1 Viral Load Quantitative Test is to quantify the BCR-ABL1 gene levels in the blood of CML patients. This helps in assessing the effectiveness of treatment, determining if a patient has achieved a major molecular response, and monitoring for any signs of disease recurrence. It is a key tool in personalized medicine for CML management.
How to Prepare
- Sign the consent form provided
- Bring relevant medical records and previous test reports
- Inform the healthcare provider about any medications or recent treatments
- Ensure the sample is collected in a sterile environment
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for monitoring CML patients on therapy to assess molecular response and guide treatment decisions, helping to detect early signs of disease recurrence."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Samples not properly labeled or stored
- Contaminated samples
Understanding Your Results
BCR-ABL1/ABL1 ratio <0.1%
Major molecular response, indicating effective treatment control.
BCR-ABL1/ABL1 ratio 0.1% to 1%
Minor molecular response, may require treatment adjustment.
BCR-ABL1/ABL1 ratio >1%
Poor response or disease recurrence, urgent medical consultation needed.
Consult a doctor if test results show elevated BCR-ABL1 levels, if symptoms of CML persist or worsen, or if there are concerns about treatment effectiveness.
Limitations
- ⚠False negatives may occur if gene levels are below detection limits
- ⚠False positives due to technical errors or contamination
- ⚠Does not provide information on other genetic mutations
- ⚠Requires specialized laboratory equipment and expertise
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Rare risk of infection or fainting
- ●No significant long-term risks associated with the test
Interfering Factors
- ●Hemolyzed blood samples
- ●Improper sample handling or storage
- ●Contamination during sample processing
- ●Recent blood transfusions affecting gene levels
Compare With Similar Tests
| Test | CML MRD1 Viral Load Quantitative Test | Complete Blood Count (CBC) | Bone Marrow Biopsy | BCR-ABL1 Mutation Analysis | Cytogenetic Analysis |
|---|---|---|---|---|---|
| Comparison | CML MRD1 Viral Load Quantitative Test | CBC measures overall blood cell counts but does not detect BCR-ABL1 gene levels. | Bone marrow biopsy provides cellular details but is invasive; MRD test is less invasive and quantitative. | Mutation analysis identifies specific gene changes, while MRD test quantifies overall gene levels. | Cytogenetic analysis examines chromosome abnormalities but is less sensitive for minimal residual disease. |
Frequently Asked Questions
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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