Cortisone : Cortisol Ratio Test
Short Name: Cortisone Cortisol Ratio
Also known as: Cortisone to Cortisol Ratio, Adrenal Hormone Ratio Test
Cortisone : Cortisol Ratio Test test available at DNA Labs India for ₹2,925. Uses LC-MS/MS on Serum samples. Results in Results are typically available within 3-5 business days after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Ramarao Paidisetty
Consultant Biochemist · Reg: 21504
Last reviewed: September 7, 2026
Overview
To measure cortisone and cortisol levels in the blood to evaluate adrenal function, diagnose hormonal imbalances, and guide treatment for conditions like Cushing's syndrome or Addison's disease.
- Test Code
- 370
- Price
- ₹2,925
- Sample Type
- Serum
- Result Time
- Results are typically available within 3-5 business days after sample collection.
- Fasting Required
- Yes
- Method
- LC-MS/MS
Sample Collection
Overnight fasting is preferred. Avoid strenuous exercise and stress before the test. Inform your doctor about any medications, as some can affect results.
Method: Venipuncture
Laboratory Analysis
A healthcare professional will collect a blood sample from a vein in your arm using a needle. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities, but avoid heavy lifting for a few hours.
Timeline: Results are typically available within 3-5 business days after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
To measure cortisone and cortisol levels in the blood to evaluate adrenal function, diagnose hormonal imbalances, and guide treatment for conditions like Cushing's syndrome or Addison's disease.
How to Prepare
- Fast overnight (8-12 hours) before sample collection
- Give sample between 8-10 am or 4-6 pm due to diurnal variation
- Specify time and date on specimen container and test request form
- Ship sample refrigerated or frozen to maintain stability
Doctor's Notes
Reviewed by Dr Ramarao Paidisetty — MBBS, MD (Biochemistry) · Reg. No. 21504
"This test is crucial for evaluating adrenal function, especially in patients with symptoms of hormonal imbalance. Early diagnosis can guide effective management of conditions like Cushing's syndrome or Addison's disease."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic samples
- Incorrect sample type or container
- Sample collected at wrong time without specification
- Insufficient sample volume
Understanding Your Results
High Cortisol with Low Cortisone
Low Cortisol with High Cortisone
Normal Ratio with Abnormal Levels
Elevated Ratio
Consult a healthcare provider if you experience symptoms like unexplained weight changes, chronic fatigue, or mood swings, or if test results are abnormal for proper diagnosis and management.
Limitations
- ⚠Single measurement may not capture diurnal variations; multiple samples might be needed
- ⚠Results should be interpreted in clinical context with other tests
- ⚠Not suitable for diagnosing all adrenal disorders without additional investigations
Risks & Considerations
- ●Minor pain or bruising at the blood draw site
- ●Rare risk of infection or dizziness
Interfering Factors
- ●Stress and physical activity
- ●Medications such as corticosteroids or oral contraceptives
- ●Time of day due to diurnal variation
- ●Pregnancy and menstrual cycle
- ●Recent surgery or illness
Compare With Similar Tests
| Test | Cortisone : Cortisol Ratio Test | Cortisol Test | ACTH Stimulation Test | DHEA-S Test |
|---|---|---|---|---|
| Comparison | Cortisone : Cortisol Ratio Test |
Frequently Asked Questions
What is the Cortisone Cortisol Ratio Test?
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