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Cortisone Serum Test

DNA Labs India | ISO 9001:2015 Certified

Cortisone Serum Test

Short Name: Cortisone Serum

Also known as: Serum Cortisol Test, Cortisol Serum Assay

Cortisone Serum Test test available at DNA Labs India for ₹2,925. Uses LC-MS/MS on Serum samples. Results in Sample collection on Monday or Thursday by 9 am; reports delivered on Wednesday or Saturday via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.

Endocrinology TestAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

The Cortisone Serum Test is performed to measure cortisol levels in the blood, aiding in the diagnosis and monitoring of adrenal gland disorders such as Cushing's syndrome and Addison's disease. It helps evaluate symptoms like weight gain, fatigue, and high blood pressure, guiding appropriate medical interventions.

Test Code
359
Price
₹2,925
Sample Type
Serum
Result Time
Sample collection on Monday or Thursday by 9 am; reports delivered on Wednesday or Saturday via online portal, email, or WhatsApp.
Fasting Required
Yes
Method
LC-MS/MS
Step 1

Sample Collection

Overnight fasting is preferred. Avoid stress, strenuous activity, and certain medications as advised by your doctor. Inform the technician about any ongoing treatments.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm by a trained technician. The process typically takes a few minutes.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Minor bruising or discomfort may occur, which usually resolves quickly. Resume normal activities unless otherwise instructed.

Timeline: Sample collection on Monday or Thursday by 9 am; reports delivered on Wednesday or Saturday via online portal, email, or WhatsApp.

Patient Instructions

1
Before the Test:Follow fasting instructions and avoid stress. Inform your doctor about all medications and supplements you are taking.
2
During the Test:The blood draw is a routine procedure with minimal discomfort. A technician will collect the sample from a vein in your arm.
3
After the Test:You may resume normal activities. Apply pressure to the puncture site if needed. Results will be available as per the turnaround time.

About This Test

Who Should Get This Test

The Cortisone Serum Test is performed to measure cortisol levels in the blood, aiding in the diagnosis and monitoring of adrenal gland disorders such as Cushing's syndrome and Addison's disease. It helps evaluate symptoms like weight gain, fatigue, and high blood pressure, guiding appropriate medical interventions.

How to Prepare

  • Take sample between 8-10 am or 4-6 pm to account for diurnal variation
  • Specify exact time and date on specimen container and test request form
  • Ship sample refrigerated or frozen to maintain stability
  • Use only Red Top (No Additive) tubes; avoid SST gel barrier tubes

Doctor's Notes

Reviewed by — MBBS, MD (Biochemistry) · Reg. No. 21504

"Cortisone Serum Test is essential for evaluating adrenal gland function. Abnormal cortisol levels can indicate conditions like Cushing's syndrome or Addison's disease, requiring prompt medical attention for proper management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerRed Top (No Additive) tube. Do not use SST gel barrier tubes.
Collection MethodVenipuncture

Sample Stability

Room Temperature8 hours
Refrigerator7 days
Frozen7 weeks
Sample Rejection Criteria:
  • Improper sample type (e.g., SST gel barrier tubes)
  • Incorrect timing of collection
  • Insufficient sample volume
  • Contaminated or hemolyzed sample

Understanding Your Results

Cortisol levels vary throughout the day, with higher levels in the morning and lower in the evening. Abnormally high or low levels may indicate adrenal gland disorders, but interpretation should consider clinical context and additional tests.
📊

May indicate Cushing's syndrome, chronic stress, obesity, or other conditions. Symptoms include weight gain, high blood pressure, and skin changes.

Action: Consult an endocrinologist for further evaluation and possible additional tests like dexamethasone suppression test.

Level: High Cortisol

📊

May indicate Addison's disease or adrenal insufficiency. Symptoms include fatigue, weight loss, and low blood pressure.

Action: Seek immediate medical attention for diagnosis and treatment, which may include hormone replacement therapy.

Level: Low Cortisol

⚠️ When to Consult a Doctor:

If you experience symptoms such as unexplained weight gain, persistent fatigue, muscle weakness, or if test results are abnormal, consult an endocrinologist or healthcare provider for a comprehensive evaluation.

Limitations

  • Single measurement may not capture diurnal variation fully
  • Results may require correlation with clinical symptoms and other tests
  • Not definitive for diagnosis alone; additional tests often needed

Risks & Considerations

  • Minor pain or bruising at the puncture site
  • Rarely, infection or dizziness
  • Minimal risk associated with blood draw

Interfering Factors

  • Stress
  • Medications (e.g., steroids, oral contraceptives)
  • Time of day (diurnal variation)
  • Pregnancy
  • Intense physical activity

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Frequently Asked Questions

What is the Cortisone Serum Test?
The Cortisone Serum Test measures the level of cortisol hormone in the blood, which is produced by the adrenal glands and helps regulate stress response, metabolism, and blood sugar.
Why is the Cortisone Serum Test done?
It is done to diagnose adrenal gland disorders such as Cushing's syndrome and Addison's disease, especially if you have symptoms like weight gain, fatigue, or high blood pressure.
How is the test performed?
A blood sample is drawn from a vein in your arm, typically in the morning or afternoon to account for diurnal variation. The process is quick and minimally invasive.
Is fasting required for the Cortisone Serum Test?
Yes, overnight fasting is preferred for accuracy. You may be asked to avoid eating or drinking anything except water for 8-12 hours before the test.
What are the normal cortisol levels?
Normal cortisol levels vary by time of day. Morning levels are typically 5-25 µg/dL, and afternoon levels are 3-16 µg/dL. Reference ranges may vary slightly by lab.
What do high cortisol levels indicate?
High cortisol levels may indicate conditions like Cushing's syndrome, chronic stress, obesity, or certain medications. Symptoms include weight gain, high blood pressure, and skin changes.
What do low cortisol levels indicate?
Low cortisol levels may suggest Addison's disease or adrenal insufficiency, leading to symptoms like fatigue, weight loss, and low blood pressure. Immediate medical attention is recommended.
Are there any risks associated with the test?
The test is generally safe with minimal risks such as minor bruising or pain at the puncture site. Serious complications like infection are rare.
How long does it take to get the results?
Results are typically available within 2-3 days. Samples collected on Monday or Thursday by 9 am have reports on Wednesday or Saturday, delivered via online portal, email, or WhatsApp.
Can the test be done at home?
Yes, DNA Labs India offers free home sample collection for the Cortisone Serum Test in many cities across India. You can book online for convenient service.
What is the cost of the Cortisone Serum Test in India?
The cost of the Cortisone Serum Test at DNA Labs India is INR 2925, which includes home sample collection and report delivery.
How should I prepare for the test?
Prepare by fasting overnight, avoiding stress and strenuous activity. Inform your doctor about any medications, and ensure the sample is taken at the specified time for accurate results.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

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