D Dimer Quantitative Test
Short Name: D-Dimer
Also known as: D-Dimer Test, Fibrin Degradation Fragment D-Dimer, D-Dimer FDP, Fragment D-dimer Quantitative, Fibrin Split Products D-Dimer
D Dimer Quantitative Test test available at DNA Labs India for ₹1,404. Uses Immunoturbidimetry on Whole Blood (Plasma) samples. Results in Results are typically available within 24 hours of sample receipt at the laboratory. Digital reports can be accessed through the online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Lakshmayya Patchava
Consultant - Internal Medicine · Reg: AMC4924
Last reviewed: September 7, 2026
Overview
The D Dimer Quantitative Test is primarily used to help detect the presence of an inappropriate or excessive blood clot (thrombus) in the body. It is most commonly ordered to evaluate patients for deep vein thrombosis (DVT), pulmonary embolism (PE), and disseminated intravascular coagulation (DIC). The test serves as an effective screening tool, particularly in ruling out thromboembolic disease when clinical suspicion is low. Additionally, it is used to monitor the effectiveness of anticoagulant therapy and to assess the risk of recurrent thrombotic events. The D-Dimer test is not diagnostic on its own but is a critical component of a comprehensive diagnostic strategy that includes clinical assessment, risk stratification, and imaging studies.
- Test Code
- 475
- CPT Code
- 85379
- ICD Code
- D68.9
- Price
- ₹1,404
- Sample Type
- Whole Blood (Plasma)
- Result Time
- Results are typically available within 24 hours of sample receipt at the laboratory. Digital reports can be accessed through the online portal, email, or WhatsApp.
- Fasting Required
- Yes
- Method
- Immunoturbidimetry
Sample Collection
Overnight fasting is preferred. Ensure the Coagulation Requisition Form (Form 15) is duly filled and available at the time of sample collection. Inform the phlebotomist about any anticoagulant medications you are currently taking. Avoid strenuous physical activity before the test.
Method: Venipuncture
Laboratory Analysis
A venipuncture will be performed, typically from a vein in the arm. Approximately 3 mL of blood will be collected into a Blue Top (Sodium Citrate) tube. The tube must be mixed thoroughly by gentle inversion 3-4 times immediately after collection to prevent clotting within the tube.
Report Delivery
Apply gentle pressure on the puncture site with a cotton ball or bandage for a few minutes to prevent bruising. There are no significant restrictions after sample collection. You may resume normal activities immediately.
Timeline: Results are typically available within 24 hours of sample receipt at the laboratory. Digital reports can be accessed through the online portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
The D Dimer Quantitative Test is primarily used to help detect the presence of an inappropriate or excessive blood clot (thrombus) in the body. It is most commonly ordered to evaluate patients for deep vein thrombosis (DVT), pulmonary embolism (PE), and disseminated intravascular coagulation (DIC). The test serves as an effective screening tool, particularly in ruling out thromboembolic disease when clinical suspicion is low. Additionally, it is used to monitor the effectiveness of anticoagulant therapy and to assess the risk of recurrent thrombotic events. The D-Dimer test is not diagnostic on its own but is a critical component of a comprehensive diagnostic strategy that includes clinical assessment, risk stratification, and imaging studies.
How to Prepare
- Overnight fasting is preferred for accurate results
- A duly filled Coagulation Requisition Form (Form 15) is mandatory
- 3 mL whole blood collected in 1 Blue Top (Sodium Citrate) tube
- Mix the sample thoroughly by gentle inversion immediately after collection
- Transport the sample to the lab within 4 hours of collection
- If transport within 4 hours is not possible, prepare Platelet Poor Plasma (PPP) within 1 hour by centrifuging at 3600 rpm for 15 minutes
- Transfer supernatant to a clean plastic tube and centrifuge again at 3600 rpm for 15 minutes
- Transfer the final supernatant (PPP) to a labelled clean plastic screw-capped vial and freeze immediately
- Ship frozen. Do not thaw the sample during transport
Doctor's Notes
Reviewed by Dr Lakshmayya Patchava — MBBS, MD (Internal Medicine) · Reg. No. AMC4924
"D-Dimer quantitative testing is a valuable first-line investigation when thromboembolic disease is suspected. A negative D-Dimer result, combined with a low clinical pre-test probability, can effectively rule out deep vein thrombosis and pulmonary embolism without the need for imaging studies. However, elevated D-Dimer levels are not specific to thrombosis alone and can be raised in various conditions including infection, malignancy, pregnancy, liver disease, and post-surgical states. Therefore, a positive D-Dimer result should always be interpreted in conjunction with the clinical context and followed up with appropriate imaging such as Doppler ultrasonography or CT pulmonary angiography. This test is also valuable for monitoring patients on anticoagulant therapy."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample collected in incorrect tube (not Sodium Citrate Blue Top)
- Clotted or hemolyzed sample
- Insufficient sample volume (less than 3 mL)
- Sample received without duly filled Coagulation Requisition Form (Form 15)
- Thawed frozen PPP sample
- Sample exceeding stability time limits without prior PPP preparation
Understanding Your Results
A D-Dimer level below the cutoff value (typically < 0.5 mg/L FEU) is considered normal or negative. In patients with a low-to-moderate clinical pre-test probability for DVT or PE, a negative D-Dimer result is highly useful in effectively ruling out acute thromboembolic disease. Further imaging studies are generally not required in this scenario.
Low likelihood of acute thromboembolism. Useful for ruling out DVT and PE in low-risk patients.
An elevated D-Dimer level above the cutoff value indicates increased fibrin degradation activity in the blood, which may suggest the presence of an active blood clot. However, elevated D-Dimer is not specific to thromboembolism and can be seen in many other conditions. A positive result warrants further diagnostic evaluation, including imaging studies such as Doppler ultrasonography for DVT or CT pulmonary angiography for PE.
Suggests possible thromboembolic event. Requires further investigation with imaging. May also be elevated in infection, inflammation, pregnancy, malignancy, liver disease, and post-operative states.
Consult your doctor immediately if you experience symptoms such as sudden shortness of breath, unexplained chest pain, leg pain with swelling, warmth or redness, rapid or irregular heartbeat, or lightheadedness. A positive or elevated D-Dimer result should always be discussed with a qualified physician who can correlate it with your clinical condition and recommend appropriate follow-up investigations. Do not attempt to self-diagnose or self-treat based on D-Dimer results alone.
Limitations
- ⚠D-Dimer has high sensitivity but low specificity for thromboembolic disease
- ⚠A positive result does not confirm the presence of a blood clot and requires further imaging
- ⚠Normal D-Dimer levels may not exclude thrombosis in high clinical probability cases
- ⚠Results may be elevated in many non-thrombotic conditions including infection, pregnancy, and cancer
- ⚠The test should not be used as a standalone diagnostic tool without clinical correlation
- ⚠Different assay methods may produce varying reference ranges, affecting comparability
Risks & Considerations
- ●Minor bruising or swelling at the venipuncture site
- ●Slight pain or discomfort during needle insertion
- ●Rare risk of infection at the puncture site
- ●In very rare cases, lightheadedness or fainting during blood draw
Interfering Factors
- ●Recent surgery or trauma can elevate D-Dimer levels
- ●Pregnancy naturally increases D-Dimer concentration
- ●Active infections, inflammation, or malignancy may cause false-positive results
- ●Liver disease and rheumatoid arthritis can affect D-Dimer levels
- ●Advanced age is associated with higher baseline D-Dimer levels
- ●Lipemic or hemolyzed samples may interfere with accurate measurement
- ●Recent immobilization or hospitalization can raise D-Dimer values
Compare With Similar Tests
| Test | D Dimer Quantitative Test | D Dimer Quantitative | Prothrombin Time (PT/INR) | Fibrinogen Test | FDP (Fibrin Degradation Products) |
|---|---|---|---|---|---|
| Comparison | D Dimer Quantitative Test |
Frequently Asked Questions
What is the D Dimer Quantitative Test?
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Can a normal D Dimer result rule out blood clots?
How is the D Dimer Quantitative Test performed?
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