EGFR Gene Nonsmall cell lung cancer, familial, susceptibility to NGS Genetic Test
Short Name: EGFR NGS Test
Also known as: EGFR Mutation Analysis, NSCLC EGFR Panel, EGFR Gene Sequencing
EGFR Gene Nonsmall cell lung cancer, familial, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are typically delivered within 3 to 4 weeks after sample receipt. You will be notified via email or WhatsApp when results are ready.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the EGFR gene that are associated with susceptibility to non-small cell lung cancer (NSCLC). It aids in confirming a diagnosis, assessing familial risk, and guiding personalized treatment strategies, particularly the use of EGFR-targeted therapies. NGS technology enables simultaneous analysis of multiple EGFR exons, providing comprehensive mutation profiling for better clinical decision-making.
- Test Code
- 6006
- CPT Code
- 81445
- ICD Code
- C34.90
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are typically delivered within 3 to 4 weeks after sample receipt. You will be notified via email or WhatsApp when results are ready.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation required. However, a genetic counseling session is recommended to discuss family history and implications of results.
Method: Venipuncture or fingerstick
Laboratory Analysis
Blood sample will be drawn by a trained phlebotomist. If using FTA card, a simple fingerstick is performed.
Report Delivery
No restrictions. Resume normal activities immediately.
Timeline: Reports are typically delivered within 3 to 4 weeks after sample receipt. You will be notified via email or WhatsApp when results are ready.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the EGFR gene that are associated with susceptibility to non-small cell lung cancer (NSCLC). It aids in confirming a diagnosis, assessing familial risk, and guiding personalized treatment strategies, particularly the use of EGFR-targeted therapies. NGS technology enables simultaneous analysis of multiple EGFR exons, providing comprehensive mutation profiling for better clinical decision-making.
How to Prepare
- Ensure the sample is collected in the provided EDTA tube or FTA card
- Label the sample with patient ID and date of birth
- For FTA card, allow to dry completely before sealing
- Transport at ambient temperature (15-30°C) within 24 hours
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"EGFR mutation testing is essential for personalized therapy in NSCLC. NGS provides comprehensive detection of actionable mutations, guiding targeted treatment decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Improperly labeled or unlabeled sample
- Sample received after prolonged transit time (>72 hours) without refrigeration
Understanding Your Results
Pathogenic mutation detected
Positive for EGFR mutation; targeted therapy (e.g., erlotinib, gefitinib) may be considered. Familial screening recommended.
No pathogenic mutation detected
Negative result; no EGFR-related susceptibility identified. Other genetic or environmental factors may be involved.
Variant of uncertain significance (VUS)
Further analysis or family studies may be needed to clarify clinical significance.
Consult an oncologist or genetic counselor if you have a family history of lung cancer, experience persistent respiratory symptoms, or have been diagnosed with NSCLC and are considering targeted therapy.
Limitations
- ⚠NGS may not detect large genomic rearrangements or deep intronic mutations
- ⚠Results are for research and clinical guidance; not a standalone diagnostic tool
- ⚠Variants of unknown significance may require further investigation
- ⚠Test does not cover all possible cancer-related genes
Risks & Considerations
- ●Minimal risk of bruising or infection at the blood draw site
- ●Psychological impact of learning genetic susceptibility
- ●Potential for incidental findings
Interfering Factors
- ●Insufficient DNA quantity or quality
- ●Contamination during sample collection
- ●Recent blood transfusion (within 2 weeks)
- ●Bone marrow transplant history
- ●Improper storage or transport of sample
Compare With Similar Tests
| Test | EGFR Gene Nonsmall cell lung cancer, familial, susceptibility to NGS Genetic Test | PCR-based EGFR Mutation Test | Sanger Sequencing | NGS (This Test) |
|---|---|---|---|---|
| Comparison | EGFR Gene Nonsmall cell lung cancer, familial, susceptibility to NGS Genetic Test |
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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